GO Term : GO:0098748 endocytic adaptor activity GO

Namespace:  molecular_function Obsolete:  false
description  The binding activity of a molecule that brings together two or more protein molecules, or a protein and another macromolecule or complex as a key step in receptor mediated endocytosis.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

13 Parents

Identifier Name Description
GO:0005515 protein binding Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
GO:0006810 transport The directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore.
GO:0005488 binding The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.
GO:0016192 vesicle-mediated transport A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane.
GO:0030674 protein binding, bridging The binding activity of a molecule that brings together two or more protein molecules, or a protein and another macromolecule or complex, through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way.
GO:0006897 endocytosis A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.
GO:0051179 localization Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported to or maintained in a specific location.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0051234 establishment of localization The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.
GO:0006898 receptor-mediated endocytosis An endocytosis process in which cell surface receptors ensure specificity of transport. A specific receptor on the cell surface binds tightly to the extracellular macromolecule (the ligand) that it recognizes; the plasma-membrane region containing the receptor-ligand complex then undergoes endocytosis, forming a transport vesicle containing the receptor-ligand complex and excluding most other plasma-membrane proteins. Receptor-mediated endocytosis generally occurs via clathrin-coated pits and vesicles.
GO:0060090 binding, bridging The binding activity of a molecule that brings together two or more molecules through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way.
GO:0098748 endocytic adaptor activity The binding activity of a molecule that brings together two or more protein molecules, or a protein and another macromolecule or complex as a key step in receptor mediated endocytosis.

13 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0098748 GO:0035615
part of GO:0006898 GO:0098748
is_a GO:0030674 GO:0098748
is_a GO:0005515 GO:0098748
is_a GO:0003674 GO:0098748
part of GO:0051234 GO:0098748
part of GO:0051179 GO:0098748
part of GO:0006897 GO:0098748
is_a GO:0060090 GO:0098748
is_a GO:0005488 GO:0098748
part of GO:0006810 GO:0098748
part of GO:0008150 GO:0098748
part of GO:0016192 GO:0098748

0 Synonyms