GO Term : GO:0032081 negative regulation of Type II site-specific deoxyribonuclease activity GO
Namespace:  biological_process Obsolete:  false
description  Any process that stops or reduces the rate of Type II restriction endodeoxyribonuclease activity.
Paste the following link

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

63 Parents

Identifier Name Description
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016787 hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.
GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acids by creating internal breaks to yield 5'-phosphomonoesters.
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0044237 cellular metabolic process The chemical reactions and pathways by which individual cells transform chemical substances.
GO:0016788 hydrolase activity, acting on ester bonds Catalysis of the hydrolysis of any ester bond.
GO:0004518 nuclease activity Catalysis of the hydrolysis of ester linkages within nucleic acids.
GO:0004519 endonuclease activity Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks.
GO:0006807 nitrogen compound metabolic process The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen, including (but not limited to) nitrogen fixation, nitrification, denitrification, assimilatory/dissimilatory nitrate reduction and the interconversion of nitrogenous organic matter and ammonium.
GO:0006139 nucleobase-containing compound metabolic process Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids.
GO:0071704 organic substance metabolic process The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon.
GO:0006259 DNA metabolic process Any cellular metabolic process involving deoxyribonucleic acid. This is one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides.
GO:0044238 primary metabolic process The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
GO:0006725 cellular aromatic compound metabolic process The chemical reactions and pathways involving aromatic compounds, any organic compound characterized by one or more planar rings, each of which contains conjugated double bonds and delocalized pi electrons, as carried out by individual cells.
GO:0050790 regulation of catalytic activity Any process that modulates the activity of an enzyme.
GO:0043086 negative regulation of catalytic activity Any process that stops or reduces the activity of an enzyme.
GO:0004536 deoxyribonuclease activity Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid.
GO:0009036 Type II site-specific deoxyribonuclease activity Catalysis of the endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates and 3' hydroxyls. Cleavage is dependent on the presence in the DNA of a specific recognition site; cleavage occurs at or very near this recognition site.
GO:0044260 cellular macromolecule metabolic process The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0004520 endodeoxyribonuclease activity Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0090304 nucleic acid metabolic process Any cellular metabolic process involving nucleic acids.
GO:0034641 cellular nitrogen compound metabolic process The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells.
GO:1901360 organic cyclic compound metabolic process The chemical reactions and pathways involving organic cyclic compound.
GO:0046483 heterocycle metabolic process The chemical reactions and pathways involving heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings).
GO:0043170 macromolecule metabolic process The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0090305 nucleic acid phosphodiester bond hydrolysis The nucleic acid metabolic process in which the phosphodiester bonds between nucleotides are cleaved by hydrolysis.
GO:0065007 biological regulation Any process that modulates a measurable attribute of any biological process, quality or function.

94 Relations

Relationship
Parent Term . Identifier
Child Term . Identifier
negatively regulates GO:0009036 GO:0032081
is_a GO:0032085 GO:0032081
is_a GO:0032073 GO:0032081
is_a GO:0065007 GO:0032081
negatively regulates GO:0009036 GO:0032081
negatively regulates GO:0006139 GO:0032081
is_a GO:0010605 GO:0032081
negatively regulates GO:0006259 GO:0032081
regulates GO:0006725 GO:0032081
is_a GO:0032078 GO:0032081
negatively regulates GO:0004518 GO:0032081
negatively regulates GO:0003824 GO:0032081
negatively regulates GO:0034641 GO:0032081
is_a GO:0032074 GO:0032081
negatively regulates GO:0004519 GO:0032081
is_a GO:0032076 GO:0032081
is_a GO:0032071 GO:0032081
regulates GO:0016893 GO:0032081
is_a GO:0032070 GO:0032081
regulates GO:0006807 GO:0032081
is_a GO:0032072 GO:0032081
regulates GO:0008150 GO:0032081
regulates GO:0090305 GO:0032081
regulates GO:0090304 GO:0032081
regulates GO:0044238 GO:0032081
regulates GO:0071704 GO:0032081
regulates GO:0044237 GO:0032081
negatively regulates GO:0016893 GO:0032081
regulates GO:0016888 GO:0032081
is_a GO:0043086 GO:0032081

7 Synonyms

Name Type
negative regulation of Type II restriction endodeoxyribonuclease activity synonym
inhibition of Type II restriction endodeoxyribonuclease activity synonym
Type II restriction enzyme inhibitor synonym
Type II restriction endodeoxyribonuclease inhibitor synonym
down regulation of Type II restriction endodeoxyribonuclease activity synonym
downregulation of Type II restriction endodeoxyribonuclease activity synonym
down-regulation of Type II restriction endodeoxyribonuclease activity synonym