GO Term : GO:0031462 Cul2-RING ubiquitin ligase complex GO

Namespace:  cellular_component Obsolete:  false
description  A ubiquitin ligase complex in which a cullin from the Cul2 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by an elongin-BC adaptor and a SOCS/BC box protein.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

12 Parents

Identifier Name Description
GO:0043234 protein complex A stable macromolecular complex composed (only) of two or more polypeptide subunits along with any covalently attached molecules (such as lipid anchors or oligosaccharide) or non-protein prosthetic groups (such as nucleotides or metal ions). Prosthetic group in this context refers to a tightly bound cofactor. The component polypeptide subunits may be identical.
GO:0005622 intracellular The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
GO:0000151 ubiquitin ligase complex A protein complex that includes a ubiquitin-protein ligase and enables ubiquitin protein ligase activity. The complex also contains other proteins that may confer substrate specificity on the complex.
GO:0031461 cullin-RING ubiquitin ligase complex Any ubiquitin ligase complex in which the catalytic core consists of a member of the cullin family and a RING domain protein; the core is associated with one or more additional proteins that confer substrate specificity.
GO:1902494 catalytic complex A protein complex which is capable of catalytic activity.
GO:0044464 cell part Any constituent part of a cell, the basic structural and functional unit of all organisms.
GO:0044424 intracellular part Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
GO:0032991 macromolecular complex A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.
GO:0005575 cellular_component The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.
GO:0005623 cell The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
GO:1990234 transferase complex A protein complex capable of catalyzing the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor).
GO:0031462 Cul2-RING ubiquitin ligase complex A ubiquitin ligase complex in which a cullin from the Cul2 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by an elongin-BC adaptor and a SOCS/BC box protein.

13 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0031461 GO:0031462
is_a GO:1990234 GO:0031462
part of GO:0044464 GO:0031462
is_a GO:1902494 GO:0031462
part of GO:0005575 GO:0031462
is_a GO:0044424 GO:0031462
is_a GO:0005575 GO:0031462
is_a GO:0000151 GO:0031462
part of GO:0005622 GO:0031462
part of GO:0005623 GO:0031462
is_a GO:0044464 GO:0031462
is_a GO:0032991 GO:0031462
is_a GO:0043234 GO:0031462

8 Synonyms

Name Type
CRL2 complex synonym
CDL2 complex synonym
ECS complex synonym
cullin-RING ligase 2 synonym
VBC complex synonym
SCF2 complex synonym
EC2S complex synonym
CBC complex synonym