GO Term : GO:0008559 xenobiotic-transporting ATPase activity GO
Namespace:  molecular_function Obsolete:  false
description  Catalysis of the reaction: ATP + H2O + xenobiotic(in) = ADP + phosphate + xenobiotic(out).
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0 Cross References

1 Data Sets

Name URL
InterPro domain GO annotations  

1 Ontology

Name
GO

2 Ontology Annotations

GO Term Gene Name
GO:0008559 IPR030244
GO:0008559 IPR030258

38 Parents

Identifier Name Description
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016787 hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.
GO:0006810 transport The directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore.
GO:0016887 ATPase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
GO:0042626 ATPase activity, coupled to transmembrane movement of substances Catalysis of the reaction: ATP + H2O = ADP + phosphate, to directly drive the active transport of a substance across a membrane.
GO:0055085 transmembrane transport The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other
GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances Catalysis of the hydrolysis of an acid anhydride to directly drive the transport of a substance across a membrane.
GO:0006855 drug transmembrane transport The process in which a drug is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
GO:0015238 drug transmembrane transporter activity Enables the directed movement of a drug from one side of a membrane to the other. A drug is any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease.
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0022857 transmembrane transporter activity Enables the transfer of a substance from one side of a membrane to the other.
GO:0005215 transporter activity Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells.
GO:0016817 hydrolase activity, acting on acid anhydrides Catalysis of the hydrolysis of any acid anhydride.
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides Catalysis of the hydrolysis of any acid anhydride which contains phosphorus.
GO:0016462 pyrophosphatase activity Catalysis of the hydrolysis of a pyrophosphate bond between two phosphate groups, leaving one phosphate on each of the two fragments.
GO:0042623 ATPase activity, coupled Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction directly drives some other reaction, for example ion transport across a membrane.
GO:0017111 nucleoside-triphosphatase activity Catalysis of the reaction: a nucleoside triphosphate + H2O = nucleoside diphosphate + phosphate.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0044763 single-organism cellular process Any process that is carried out at the cellular level, occurring within a single organism.
GO:0044699 single-organism process A biological process that involves only one organism.
GO:0051179 localization Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported to or maintained in a specific location.
GO:1902578 single-organism localization A localization which involves only one organism.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0051234 establishment of localization The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.
GO:0044765 single-organism transport The directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore, involving a single organism.
GO:0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.
GO:0022804 active transmembrane transporter activity Catalysis of the transfer of a specific substance or related group of substances from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction.
GO:0042221 response to chemical Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.
GO:0043492 ATPase activity, coupled to movement of substances Catalysis of the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of a substance.

37 Relations

Relationship
Parent Term . Identifier
Child Term . Identifier
is_a GO:0015238 GO:0008559
is_a GO:0042910 GO:0008559
is_a GO:0042626 GO:0008559
part of GO:0006855 GO:0008559
is_a GO:0022804 GO:0008559
is_a GO:0016820 GO:0008559
is_a GO:0016787 GO:0008559
part of GO:0006810 GO:0008559
is_a GO:0016887 GO:0008559
is_a GO:0016462 GO:0008559
is_a GO:0017111 GO:0008559
is_a GO:0015399 GO:0008559
is_a GO:0003824 GO:0008559
part of GO:0042908 GO:0008559
part of GO:0050896 GO:0008559
part of GO:0015893 GO:0008559
part of GO:0042221 GO:0008559
part of GO:0044763 GO:0008559
part of GO:1902578 GO:0008559
part of GO:0044765 GO:0008559
part of GO:0051234 GO:0008559
part of GO:0051179 GO:0008559
is_a GO:0042623 GO:0008559
is_a GO:0090484 GO:0008559
is_a GO:0022857 GO:0008559
is_a GO:0003674 GO:0008559
is_a GO:0005215 GO:0008559
part of GO:0008152 GO:0008559
part of GO:0055085 GO:0008559
part of GO:0008150 GO:0008559

13 Synonyms

Name Type
ATP phosphohydrolase (steroid-exporting) synonym
ATP phosphohydrolase (xenobiotic-exporting) synonym
MDR protein synonym
multidrug resistance exporter synonym
multidrug-resistance protein synonym
P-glycoprotein synonym
PDR protein synonym
pleiotropic-drug-resistance protein synonym
steroid ABC transporter synonym
steroid-transporting ATPase activity synonym
xenobiotic ABC transporter synonym
GO:0005226 alt_id
GO:0008560 alt_id