GO Term : GO:0005260 channel-conductance-controlling ATPase activity GO

Namespace:  molecular_function Obsolete:  false
description  Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate. An animal enzyme that is active in forming a chloride channel, the absence of which brings about cystic fibrosis. It is also involved in the functioning of other transmembrane channels.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

50 Parents

Identifier Name Description
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016787 hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.
GO:0006810 transport The directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore.
GO:0016887 ATPase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
GO:0042626 ATPase activity, coupled to transmembrane movement of substances Catalysis of the reaction: ATP + H2O = ADP + phosphate, to directly drive the active transport of a substance across a membrane.
GO:0055085 transmembrane transport The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other
GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances Catalysis of the hydrolysis of an acid anhydride to directly drive the transport of a substance across a membrane.
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0022857 transmembrane transporter activity Enables the transfer of a substance from one side of a membrane to the other.
GO:0005215 transporter activity Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells.
GO:0022891 substrate-specific transmembrane transporter activity Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other.
GO:0005216 ion channel activity Enables the facilitated diffusion of an ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. May be either selective (it enables passage of a specific ion only) or non-selective (it enables passage of two or more ions of same charge but different size).
GO:0006811 ion transport The directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0034220 ion transmembrane transport A process in which an ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
GO:0016817 hydrolase activity, acting on acid anhydrides Catalysis of the hydrolysis of any acid anhydride.
GO:0015075 ion transmembrane transporter activity Enables the transfer of an ion from one side of a membrane to the other.
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides Catalysis of the hydrolysis of any acid anhydride which contains phosphorus.
GO:0006820 anion transport The directed movement of anions, atoms or small molecules with a net negative charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0016462 pyrophosphatase activity Catalysis of the hydrolysis of a pyrophosphate bond between two phosphate groups, leaving one phosphate on each of the two fragments.
GO:0015103 inorganic anion transmembrane transporter activity Enables the transfer of inorganic anions from one side of a membrane to the other. Inorganic anions are atoms or small molecules with a negative charge which do not contain carbon in covalent linkage.
GO:0006821 chloride transport The directed movement of chloride into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015267 channel activity Enables the energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules.
GO:0042623 ATPase activity, coupled Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction directly drives some other reaction, for example ion transport across a membrane.
GO:0008509 anion transmembrane transporter activity Enables the transfer of a negatively charged ion from one side of a membrane to the other.
GO:0017111 nucleoside-triphosphatase activity Catalysis of the reaction: a nucleoside triphosphate + H2O = nucleoside diphosphate + phosphate.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0015698 inorganic anion transport The directed movement of inorganic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Inorganic anions are atoms or small molecules with a negative charge which do not contain carbon in covalent linkage.
GO:0098656 anion transmembrane transport A process in which an anion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
GO:0044763 single-organism cellular process Any process that is carried out at the cellular level, occurring within a single organism.
GO:0044699 single-organism process A biological process that involves only one organism.

49 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0042626 GO:0005260
is_a GO:0005254 GO:0005260
is_a GO:0005253 GO:0005260
part of GO:0044699 GO:0005260
is_a GO:0015399 GO:0005260
is_a GO:0016820 GO:0005260
is_a GO:0016787 GO:0005260
part of GO:1902476 GO:0005260
is_a GO:0016887 GO:0005260
is_a GO:0003824 GO:0005260
part of GO:1902578 GO:0005260
part of GO:0006820 GO:0005260
part of GO:0006821 GO:0005260
part of GO:0098660 GO:0005260
part of GO:0098661 GO:0005260
is_a GO:0022804 GO:0005260
part of GO:0015698 GO:0005260
is_a GO:0022803 GO:0005260
part of GO:0051234 GO:0005260
part of GO:0051179 GO:0005260
is_a GO:0015108 GO:0005260
is_a GO:0015405 GO:0005260
part of GO:0044763 GO:0005260
part of GO:0044765 GO:0005260
is_a GO:0016817 GO:0005260
is_a GO:0022838 GO:0005260
is_a GO:0016818 GO:0005260
is_a GO:0015267 GO:0005260
is_a GO:0015103 GO:0005260
part of GO:0008150 GO:0005260

3 Synonyms

Name Type
ATP phosphohydrolase (channel-conductance-controlling) synonym
cystic fibrosis transmembrane conductance regulator synonym
cystic-fibrosis membrane-conductance-regulating protein activity synonym