GO Term : GO:0034260 negative regulation of GTPase activity GO
Namespace:  biological_process Obsolete:  false
description  Any process that stops or reduces the rate of GTP hydrolysis by a GTPase.
Paste the following link

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

23 Parents

Identifier Name Description
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016787 hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.
GO:0003924 GTPase activity Catalysis of the reaction: GTP + H2O = GDP + phosphate.
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0043087 regulation of GTPase activity Any process that modulates the rate of GTP hydrolysis by a GTPase.
GO:0016817 hydrolase activity, acting on acid anhydrides Catalysis of the hydrolysis of any acid anhydride.
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides Catalysis of the hydrolysis of any acid anhydride which contains phosphorus.
GO:0016462 pyrophosphatase activity Catalysis of the hydrolysis of a pyrophosphate bond between two phosphate groups, leaving one phosphate on each of the two fragments.
GO:0050790 regulation of catalytic activity Any process that modulates the activity of an enzyme.
GO:0043086 negative regulation of catalytic activity Any process that stops or reduces the activity of an enzyme.
GO:0017111 nucleoside-triphosphatase activity Catalysis of the reaction: a nucleoside triphosphate + H2O = nucleoside diphosphate + phosphate.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0065007 biological regulation Any process that modulates a measurable attribute of any biological process, quality or function.
GO:0050789 regulation of biological process Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.
GO:0065009 regulation of molecular function Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.
GO:0009892 negative regulation of metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.
GO:0048519 negative regulation of biological process Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0044092 negative regulation of molecular function Any process that stops or reduces the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.
GO:0051336 regulation of hydrolase activity Any process that modulates the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.
GO:0051346 negative regulation of hydrolase activity Any process that stops or reduces the rate of hydrolase activity, the catalysis of the hydrolysis of various bonds.
GO:0034260 negative regulation of GTPase activity Any process that stops or reduces the rate of GTP hydrolysis by a GTPase.

36 Relations

Relationship
Parent Term . Identifier
Child Term . Identifier
part of GO:0034260 GO:0005095
negatively regulates GO:0003924 GO:0034260
is_a GO:0065007 GO:0034260
negatively regulates GO:0003924 GO:0034260
is_a GO:0051346 GO:0034260
is_a GO:0043087 GO:0034260
negatively regulates GO:0016818 GO:0034260
regulates GO:0003674 GO:0034260
negatively regulates GO:0003824 GO:0034260
is_a GO:0048519 GO:0034260
regulates GO:0016787 GO:0034260
regulates GO:0008150 GO:0034260
negatively regulates GO:0016817 GO:0034260
is_a GO:0051336 GO:0034260
is_a GO:0043086 GO:0034260
is_a GO:0008150 GO:0034260
is_a GO:0044092 GO:0034260
is_a GO:0050789 GO:0034260
regulates GO:0008152 GO:0034260
is_a GO:0050790 GO:0034260
negatively regulates GO:0003674 GO:0034260
regulates GO:0016462 GO:0034260
regulates GO:0017111 GO:0034260
is_a GO:0065009 GO:0034260
regulates GO:0003924 GO:0034260
regulates GO:0003824 GO:0034260
negatively regulates GO:0016787 GO:0034260
negatively regulates GO:0008150 GO:0034260
negatively regulates GO:0017111 GO:0034260
negatively regulates GO:0016462 GO:0034260

29 Synonyms

Name Type
down regulation of GTPase activity synonym
down regulation of regulation of Ran GTPase activity synonym
down regulation of Rho GTPase activity synonym
down regulation of Rab GTPase activity synonym
down regulation of Ras GTPase activity synonym
down-regulation of Ras GTPase activity synonym
down-regulation of regulation of Ran GTPase activity synonym
down-regulation of GTPase activity synonym
down-regulation of Rab GTPase activity synonym
downregulation of Rab GTPase activity synonym
downregulation of Ras GTPase activity synonym
down-regulation of Rho GTPase activity synonym
downregulation of GTPase activity synonym
inhibition of GTPase activity synonym
inhibition of Rab GTPase activity synonym
downregulation of regulation of Ran GTPase activity synonym
downregulation of Rho GTPase activity synonym
inhibition of Rho GTPase activity synonym
negative regulation of guanosinetriphosphatase activity synonym
inhibition of Ras GTPase activity synonym
inhibition of regulation of Ran GTPase activity synonym
negative regulation of Ras GTPase activity synonym
negative regulation of Rho GTPase activity synonym
negative regulation of Rab GTPase activity synonym
negative regulation of Ran GTPase activity synonym
GO:1902264 alt_id
GO:1902881 alt_id
GO:0034259 alt_id
GO:0034261 alt_id