GO Term : GO:0005090 Sar guanyl-nucleotide exchange factor activity GO
Namespace:  molecular_function Obsolete:  false
description  Stimulates the exchange of guanyl nucleotides associated with a GTPase of the Sar family. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase.
Paste the following link

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

50 Parents

Identifier Name Description
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016787 hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.
GO:0005515 protein binding Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
GO:0000166 nucleotide binding Interacting selectively and non-covalently with a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose.
GO:0005488 binding The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.
GO:0003924 GTPase activity Catalysis of the reaction: GTP + H2O = GDP + phosphate.
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0043087 regulation of GTPase activity Any process that modulates the rate of GTP hydrolysis by a GTPase.
GO:0016817 hydrolase activity, acting on acid anhydrides Catalysis of the hydrolysis of any acid anhydride.
GO:0019001 guanyl nucleotide binding Interacting selectively and non-covalently with guanyl nucleotides, any compound consisting of guanosine esterified with (ortho)phosphate.
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides Catalysis of the hydrolysis of any acid anhydride which contains phosphorus.
GO:0030234 enzyme regulator activity Binds to and modulates the activity of an enzyme.
GO:0016462 pyrophosphatase activity Catalysis of the hydrolysis of a pyrophosphate bond between two phosphate groups, leaving one phosphate on each of the two fragments.
GO:0032549 ribonucleoside binding Interacting selectively and non-covalently with a ribonucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked to ribose.
GO:0001882 nucleoside binding Interacting selectively and non-covalently with a nucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked either to ribose or deoxyribose.
GO:0043085 positive regulation of catalytic activity Any process that activates or increases the activity of an enzyme.
GO:0017076 purine nucleotide binding Interacting selectively and non-covalently with purine nucleotides, any compound consisting of a purine nucleoside esterified with (ortho)phosphate.
GO:0050790 regulation of catalytic activity Any process that modulates the activity of an enzyme.
GO:0005085 guanyl-nucleotide exchange factor activity Stimulates the exchange of guanyl nucleotides associated with a GTPase. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase.
GO:0036094 small molecule binding Interacting selectively and non-covalently with a small molecule, any low molecular weight, monomeric, non-encoded molecule.
GO:0017111 nucleoside-triphosphatase activity Catalysis of the reaction: a nucleoside triphosphate + H2O = nucleoside diphosphate + phosphate.
GO:0043167 ion binding Interacting selectively and non-covalently with ions, charged atoms or groups of atoms.
GO:0097367 carbohydrate derivative binding Interacting selectively and non-covalently with a carbohydrate derivative.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0065007 biological regulation Any process that modulates a measurable attribute of any biological process, quality or function.
GO:0050789 regulation of biological process Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.
GO:1901363 heterocyclic compound binding Interacting selectively and non-covalently with heterocyclic compound.
GO:0097159 organic cyclic compound binding Interacting selectively and non-covalently with an organic cyclic compound, any molecular entity that contains carbon arranged in a cyclic molecular structure.

54 Relations

Relationship
Parent Term . Identifier
Child Term . Identifier
is_a GO:0005085 GO:0005090
is_a GO:0030695 GO:0005090
negatively regulates GO:0003674 GO:0005090
has_part GO:0005488 GO:0005090
negatively regulates GO:0032553 GO:0005090
negatively regulates GO:0000166 GO:0005090
negatively regulates GO:0032555 GO:0005090
negatively regulates GO:1901363 GO:0005090
regulates GO:0016817 GO:0005090
part of GO:0065007 GO:0005090
regulates GO:0008152 GO:0005090
regulates GO:0016818 GO:0005090
part of GO:0065009 GO:0005090
part of GO:0050790 GO:0005090
regulates GO:0016787 GO:0005090
regulates GO:0008150 GO:0005090
negatively regulates GO:0043167 GO:0005090
negatively regulates GO:0043168 GO:0005090
negatively regulates GO:0032561 GO:0005090
part of GO:0019222 GO:0005090
regulates GO:0017111 GO:0005090
regulates GO:0016462 GO:0005090
negatively regulates GO:0005488 GO:0005090
part of GO:0048518 GO:0005090
regulates GO:0003674 GO:0005090
has_part GO:0003674 GO:0005090
negatively regulates GO:0001883 GO:0005090
is_a GO:0003674 GO:0005090
negatively regulates GO:0001882 GO:0005090
part of GO:0009893 GO:0005090

0 Synonyms