GO Term : GO:0004467 long-chain fatty acid-CoA ligase activity GO

Namespace:  molecular_function Obsolete:  false
description  Catalysis of the reaction: ATP + a long-chain carboxylic acid + CoA = AMP + diphosphate + an acyl-CoA; a long-chain fatty acid is a fatty acid with a chain length between C13 and C22.

0 Cross References

1 Data Sets

Name URL
InterPro domain GO annotations  

1 Ontology

Name
GO

7 Ontology Annotations

GO Term Gene Name
GO:0004467 IPR030302
GO:0004467 IPR030304
GO:0004467 IPR030305
GO:0004467 IPR030307
GO:0004467 IPR030308
GO:0004467 IPR030309
GO:0004467 IPR030310

24 Parents

Identifier Name Description
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0006629 lipid metabolic process The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0016874 ligase activity Catalysis of the joining of two substances, or two groups within a single molecule, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
GO:0019752 carboxylic acid metabolic process The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-).
GO:0044237 cellular metabolic process The chemical reactions and pathways by which individual cells transform chemical substances.
GO:0006631 fatty acid metabolic process The chemical reactions and pathways involving fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.
GO:0071704 organic substance metabolic process The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon.
GO:0006082 organic acid metabolic process The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage.
GO:0044238 primary metabolic process The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0044255 cellular lipid metabolic process The chemical reactions and pathways involving lipids, as carried out by individual cells.
GO:0044763 single-organism cellular process Any process that is carried out at the cellular level, occurring within a single organism.
GO:0044699 single-organism process A biological process that involves only one organism.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0044710 single-organism metabolic process A metabolic process - chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances - which involves a single organism.
GO:0032787 monocarboxylic acid metabolic process The chemical reactions and pathways involving monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-).
GO:0043436 oxoacid metabolic process The chemical reactions and pathways involving any oxoacid; an oxoacid is a compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons).
GO:0044281 small molecule metabolic process The chemical reactions and pathways involving small molecules, any low molecular weight, monomeric, non-encoded molecule.
GO:0001676 long-chain fatty acid metabolic process The chemical reactions and pathways involving long-chain fatty acids, A long-chain fatty acid is a fatty acid with a chain length between C13 and C22.
GO:0016877 ligase activity, forming carbon-sulfur bonds Catalysis of the joining of two molecules via a carbon-sulfur bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
GO:0015645 fatty acid ligase activity Catalysis of the ligation of a fatty acid to an acceptor, coupled to the hydrolysis of ATP.
GO:0004467 long-chain fatty acid-CoA ligase activity Catalysis of the reaction: ATP + a long-chain carboxylic acid + CoA = AMP + diphosphate + an acyl-CoA; a long-chain fatty acid is a fatty acid with a chain length between C13 and C22.

26 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0015645 GO:0004467
part of GO:0001676 GO:0004467
is_a GO:0016874 GO:0004467
part of GO:0006629 GO:0004467
part of GO:0044281 GO:0004467
is_a GO:0003824 GO:0004467
part of GO:0032787 GO:0004467
part of GO:0044238 GO:0004467
part of GO:0044237 GO:0004467
part of GO:0044699 GO:0004467
part of GO:0044710 GO:0004467
part of GO:0071704 GO:0004467
part of GO:0019752 GO:0004467
part of GO:0044763 GO:0004467
part of GO:0006082 GO:0004467
part of GO:0044255 GO:0004467
part of GO:0008150 GO:0004467
part of GO:0008152 GO:0004467
is_a GO:0003674 GO:0004467
is_a GO:0016877 GO:0004467
part of GO:0006631 GO:0004467
part of GO:0009987 GO:0004467
part of GO:0043436 GO:0004467
is_a GO:0004467 GO:0090432
is_a GO:0004467 GO:0090433
is_a GO:0004467 GO:0090434

26 Synonyms

Name Type
ACS3 synonym
arachidonyl-CoA synthetase synonym
acyl-CoA synthetase activity synonym
fatty acid thiokinase (long chain) activity synonym
FAA1 synonym
LCFA synthetase activity synonym
fatty acid thiokinase (long-chain) activity synonym
long chain fatty acyl-CoA synthetase activity synonym
lignoceroyl-CoA synthase activity synonym
long-chain acyl-CoA synthetase activity synonym
long-chain acyl CoA synthetase activity synonym
long-chain acyl-CoA synthetase II synonym
long-chain acyl-CoA synthetase I synonym
long-chain fatty acid activation synonym
long-chain acyl-coenzyme A synthetase activity synonym
long-chain-fatty-acid-CoA ligase activity synonym
long-chain fatty acyl coenzyme A synthetase activity synonym
acyl-activating enzyme activity synonym
oleoyl-CoA synthetase synonym
long-chain-fatty-acyl-CoA synthetase activity synonym
palmitoyl-CoA ligase synonym
palmitoyl coenzyme A synthetase synonym
pristanoyl-CoA synthetase synonym
palmitoyl-CoA synthase synonym
thiokinase synonym
stearoyl-CoA synthetase synonym