GO Term : GO:0002484 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway GO

Namespace:  biological_process Obsolete:  false
description  The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via an ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in the ER. Class I here refers to classical class I molecules.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

9 Parents

Identifier Name Description
GO:0019882 antigen processing and presentation The process in which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0002376 immune system process Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.
GO:0048002 antigen processing and presentation of peptide antigen The process in which an antigen-presenting cell expresses peptide antigen in association with an MHC protein complex on its cell surface, including proteolysis and transport steps for the peptide antigen both prior to and following assembly with the MHC protein complex. The peptide antigen is typically, but not always, processed from an endogenous or exogenous protein.
GO:0002474 antigen processing and presentation of peptide antigen via MHC class I The process in which an antigen-presenting cell expresses a peptide antigen on its cell surface in association with an MHC class I protein complex. Class I here refers to classical class I molecules.
GO:0002483 antigen processing and presentation of endogenous peptide antigen The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC protein complex. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell.
GO:0019883 antigen processing and presentation of endogenous antigen The process in which an antigen-presenting cell expresses antigen (peptide or lipid) of endogenous origin on its cell surface in association with an MHC protein complex.
GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex. The peptide antigen is typically, but not always, processed from a whole protein. Class I here refers to classical class I molecules.
GO:0002484 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via an ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in the ER. Class I here refers to classical class I molecules.

10 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0019885 GO:0002484
is_a GO:0002474 GO:0002484
is_a GO:0008150 GO:0002484
is_a GO:0002376 GO:0002484
is_a GO:0048002 GO:0002484
is_a GO:0002483 GO:0002484
is_a GO:0019882 GO:0002484
is_a GO:0019883 GO:0002484
is_a GO:0002484 GO:0002485
is_a GO:0002484 GO:0002486

1 Synonyms

Name Type
endogenous peptide antigen processing and presentation via MHC class I via ER pathway synonym