GO Term : GO:0002095 caveolar macromolecular signaling complex GO

Namespace:  cellular_component Obsolete:  false
description  A complex composed of proteins required for beta adrenergic receptor activation of protein kinase A. It includes the Cav 12. subunit of L-type calcium channel, protein kinase A regulatory subunit 2(PKAR2), adenyl cyclase, beta-adrenergic receptor, G-alpha-S, protein phosphatase 2A (PP2A) and caveolin 3 (CAV3).

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

20 Parents

Identifier Name Description
GO:0016020 membrane A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
GO:0043234 protein complex A stable macromolecular complex composed (only) of two or more polypeptide subunits along with any covalently attached molecules (such as lipid anchors or oligosaccharide) or non-protein prosthetic groups (such as nucleotides or metal ions). Prosthetic group in this context refers to a tightly bound cofactor. The component polypeptide subunits may be identical.
GO:0005886 plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
GO:0044464 cell part Any constituent part of a cell, the basic structural and functional unit of all organisms.
GO:0032991 macromolecular complex A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.
GO:0005575 cellular_component The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.
GO:0005623 cell The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
GO:0071944 cell periphery The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures.
GO:0098796 membrane protein complex Any protein complex that is part of a membrane.
GO:0044425 membrane part Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
GO:0098797 plasma membrane protein complex Any protein complex that is part of the plasma membrane.
GO:0044459 plasma membrane part Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
GO:0098805 whole membrane Any lipid bilayer that completely encloses some structure, and all the proteins embedded in it or attached to it. Examples include the plasma membrane and most organelle membranes.
GO:0098589 membrane region A membrane that is a part of a larger membrane. Examples include the apical region of the plasma membrane of an epithelial cell and the various regions of the endoplasmic reticulum membrane.
GO:0098590 plasma membrane region A membrane that is a (regional) part of the plasma membrane.
GO:0002095 caveolar macromolecular signaling complex A complex composed of proteins required for beta adrenergic receptor activation of protein kinase A. It includes the Cav 12. subunit of L-type calcium channel, protein kinase A regulatory subunit 2(PKAR2), adenyl cyclase, beta-adrenergic receptor, G-alpha-S, protein phosphatase 2A (PP2A) and caveolin 3 (CAV3).
GO:0005901 caveola A membrane raft that forms small pit, depression, or invagination that communicates with the outside of a cell and extends inward, indenting the cytoplasm and the cell membrane. Examples include any of the minute pits or incuppings of the cell membrane formed during pinocytosis. Such caveolae may be pinched off to form free vesicles within the cytoplasm.
GO:0044853 plasma membrane raft A membrane raft that is part of the plasma membrane.
GO:0045121 membrane raft Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions.
GO:0098857 membrane microdomain A membrane region with a lipid composition that is distinct from that of the membrane regions that surround it.

23 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0098797 GO:0002095
part of GO:0005901 GO:0002095
part of GO:0005886 GO:0002095
part of GO:0005623 GO:0002095
part of GO:0044853 GO:0002095
part of GO:0005575 GO:0002095
part of GO:0098590 GO:0002095
is_a GO:0032991 GO:0002095
part of GO:0044464 GO:0002095
part of GO:0045121 GO:0002095
is_a GO:0098796 GO:0002095
part of GO:0044425 GO:0002095
part of GO:0071944 GO:0002095
part of GO:0044459 GO:0002095
is_a GO:0043234 GO:0002095
part of GO:0098805 GO:0002095
is_a GO:0044464 GO:0002095
part of GO:0098857 GO:0002095
is_a GO:0044459 GO:0002095
is_a GO:0005575 GO:0002095
part of GO:0016020 GO:0002095
is_a GO:0044425 GO:0002095
part of GO:0098589 GO:0002095

1 Synonyms

Name Type
caveolar macromolecular signalling complex synonym