GO Term : GO:0001301 progressive alteration of chromatin involved in cell aging GO

Namespace:  biological_process Obsolete:  false
description  The chromatin modification process that occurs during the lifespan of the cell that results in changes in chromatin structure. Such changes may lead to gene dysregulation and ultimately to a loss in cell homeostasis, bringing about an aging phenotype.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

16 Parents

Identifier Name Description
GO:0051276 chromosome organization A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. This term covers covalent modifications at the molecular level as well as spatial relationships among the major components of a chromosome.
GO:0016568 chromatin modification The alteration of DNA, protein, or sometimes RNA, in chromatin, which may result in changing the chromatin structure.
GO:0032502 developmental process A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition.
GO:0016043 cellular component organization A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0006325 chromatin organization Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic chromatin.
GO:0006996 organelle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
GO:0044763 single-organism cellular process Any process that is carried out at the cellular level, occurring within a single organism.
GO:0044699 single-organism process A biological process that involves only one organism.
GO:0071840 cellular component organization or biogenesis A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0043933 macromolecular complex subunit organization Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a macromolecular complex.
GO:0044767 single-organism developmental process A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition, involving only one organism.
GO:0007569 cell aging An aging process that has as participant a cell after a cell has stopped dividing. Cell aging may occur when a cell has temporarily stopped dividing through cell cycle arrest (GO:0007050) or when a cell has permanently stopped dividing, in which case it is undergoing cellular senescence (GO:0090398). May precede cell death (GO:0008219) and succeed cell maturation (GO:0048469).
GO:0007568 aging A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death (GO:0016265) and may succeed developmental maturation (GO:0021700).
GO:0001301 progressive alteration of chromatin involved in cell aging The chromatin modification process that occurs during the lifespan of the cell that results in changes in chromatin structure. Such changes may lead to gene dysregulation and ultimately to a loss in cell homeostasis, bringing about an aging phenotype.

39 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0016568 GO:0001301
part of GO:0007569 GO:0001301
part of GO:0007569 GO:0001301
is_a GO:0016568 GO:0001301
is_a GO:0016043 GO:0001301
part of GO:0009987 GO:0001301
is_a GO:0071840 GO:0001301
part of GO:0051276 GO:0001301
is_a GO:0043933 GO:0001301
part of GO:0008150 GO:0001301
part of GO:0032502 GO:0001301
part of GO:0044763 GO:0001301
part of GO:0016043 GO:0001301
is_a GO:0009987 GO:0001301
part of GO:0071840 GO:0001301
is_a GO:0006325 GO:0001301
is_a GO:0008150 GO:0001301
part of GO:0044767 GO:0001301
part of GO:0006996 GO:0001301
part of GO:0007568 GO:0001301
part of GO:0044699 GO:0001301
is_a GO:0001301 GO:0001304
is_a GO:0001301 GO:0001304
is_a GO:0001301 GO:0001305
is_a GO:0001301 GO:0001305
is_a GO:0001301 GO:0001307
is_a GO:0001301 GO:0001308
is_a GO:0001301 GO:0001310
part of GO:0001301 GO:0001311
part of GO:0001301 GO:0001312

3 Synonyms

Name Type
progressive alteration of chromatin during cell ageing synonym
age-dependent accumulation of genetic damage synonym
progressive alteration of chromatin during cell aging synonym