GO Term : GO:0000243 commitment complex GO

Namespace:  cellular_component Obsolete:  false
description  A spliceosomal complex that is formed by association of the U1 snRNP with the 5' splice site of an unspliced intron in an RNA transcript.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

22 Parents

Identifier Name Description
GO:0005634 nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
GO:0005681 spliceosomal complex Any of a series of ribonucleoprotein complexes that contain snRNA(s) and small nuclear ribonucleoproteins (snRNPs), and are formed sequentially during the spliceosomal splicing of one or more substrate RNAs, and which also contain the RNA substrate(s) from the initial target RNAs of splicing, the splicing intermediate RNA(s), to the final RNA products. During cis-splicing, the initial target RNA is a single, contiguous RNA transcript, whether mRNA, snoRNA, etc., and the released products are a spliced RNA and an excised intron, generally as a lariat structure. During trans-splicing, there are two initial substrate RNAs, the spliced leader RNA and a pre-mRNA.
GO:0005622 intracellular The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
GO:0043231 intracellular membrane-bounded organelle Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
GO:0030529 intracellular ribonucleoprotein complex An intracellular macromolecular complex containing both protein and RNA molecules.
GO:0005685 U1 snRNP A ribonucleoprotein complex that contains small nuclear RNA U1.
GO:0030532 small nuclear ribonucleoprotein complex A complex composed of RNA of the small nuclear RNA (snRNA) class and protein, found in the nucleus of a eukaryotic cell. These are typically named after the snRNA(s) they contain, e.g. U1 snRNP or U4/U6 snRNP. Many, but not all, of these complexes are involved in splicing of nuclear mRNAs.
GO:1990904 ribonucleoprotein complex A macromolecular complex containing both protein and RNA molecules.
GO:0044464 cell part Any constituent part of a cell, the basic structural and functional unit of all organisms.
GO:0044424 intracellular part Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
GO:0032991 macromolecular complex A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.
GO:0005575 cellular_component The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.
GO:0005623 cell The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
GO:0044428 nuclear part Any constituent part of the nucleus, a membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated.
GO:0043227 membrane-bounded organelle Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
GO:0043226 organelle Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane.
GO:0043229 intracellular organelle Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
GO:0044422 organelle part Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.
GO:0044446 intracellular organelle part A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.
GO:0000243 commitment complex A spliceosomal complex that is formed by association of the U1 snRNP with the 5' splice site of an unspliced intron in an RNA transcript.
GO:0005684 U2-type spliceosomal complex Any spliceosomal complex that forms during the splicing of a messenger RNA primary transcript to excise an intron that has canonical consensus sequences near the 5' and 3' ends.
GO:0097525 spliceosomal snRNP complex A ribonucleoprotein complex involved in formation of the spliceosome and composed of one or more snRNA and multiple protein components.

33 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
has_part GO:0005685 GO:0000243
is_a GO:0005684 GO:0000243
is_a GO:0044422 GO:0000243
is_a GO:0044424 GO:0000243
is_a GO:0044446 GO:0000243
has_part GO:0044428 GO:0000243
part of GO:0005575 GO:0000243
has_part GO:0044422 GO:0000243
is_a GO:0044428 GO:0000243
has_part GO:0044446 GO:0000243
has_part GO:0044424 GO:0000243
has_part GO:0044464 GO:0000243
is_a GO:0005575 GO:0000243
part of GO:0043226 GO:0000243
has_part GO:0097525 GO:0000243
part of GO:0005622 GO:0000243
is_a GO:0030529 GO:0000243
part of GO:0043227 GO:0000243
is_a GO:0044464 GO:0000243
part of GO:0043229 GO:0000243
part of GO:0005623 GO:0000243
has_part GO:1990904 GO:0000243
is_a GO:1990904 GO:0000243
has_part GO:0030529 GO:0000243
is_a GO:0032991 GO:0000243
has_part GO:0030532 GO:0000243
part of GO:0044424 GO:0000243
part of GO:0043231 GO:0000243
has_part GO:0005575 GO:0000243
part of GO:0044464 GO:0000243

3 Synonyms

Name Type
mammalian spliceosomal E complex synonym
mammalian spliceosomal complex E synonym
yeast spliceosomal complex CC synonym