Protein Domain : IPR030306

Type:  Family Name:  Solute carrier family 26 member 9
Description:  Solute carrier family 26 member 9 (SLC26A9) has been reported to have both a Cl- channel and a Cl-/HCO3- exchanger activity []. It also seems to exhibit a unique function among the SLC26 members, as its anion transport activity was shown to be coupled to cation transport (Na+/anion transport) [].SLC26A9 is predominantly expressed in the lung and stomach, and to a lower degree in kidney [, , ]. Inactivation of SLC26A9 in mice led to loss of gastric acid secretion []. In the airway, SLC26A9 mediated Cl- secretion in response to airway inflammation induced by IL-13 []. In the kidney, SLC26A9 is required for the regulation of both renal salt excretion and blood pressure []. Short Name:  SLC26A9
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0 Child Features

0 Contains

1 Cross References

Identifier
PTHR11814:SF17

0 Found In

6 GO Annotations

GO Term Gene Name
GO:0005254 IPR030306
GO:0015301 IPR030306
GO:0006811 IPR030306
GO:0006821 IPR030306
GO:0015701 IPR030306
GO:0016021 IPR030306

6 Ontology Annotations

GO Term Gene Name
GO:0005254 IPR030306
GO:0015301 IPR030306
GO:0006811 IPR030306
GO:0006821 IPR030306
GO:0015701 IPR030306
GO:0016021 IPR030306

1 Parent Features

DB identifier Type Name
IPR001902 Family SLC26A/SulP transporter

0 Proteins

7 Publications

First Author Title Year Journal Volume Pages PubMed ID
            11834742
            19365592
            17120765
            15800055
            23149824
            19004773
            22945630