1 Child Features
| DB identifier | Type | Name |
|---|---|---|
| IPR027464 | Domain | Ornithine decarboxylase, N-terminal domain |
| Type: | Domain | Name: | Orn/Lys/Arg decarboxylase, N-terminal |
| Description: | This domain has a flavodoxin-like fold, and is termed the "wing" domain because of its position in the overall 3D structure. Ornithine decarboxylase from Lactobacillus 30a (L30a OrnDC, ) is representative of the large, pyridoxal-5'-phosphate-dependent decarboxylases that act on lysine, arginine or ornithine. The crystal structure of the L30a OrnDC has been solved to 3.0 A resolution. Six dimers related by C6 symmetry compose the enzymatically activedodecamer (approximately 106Da). Each monomer of L30a OrnDC can be described in terms of five sequential folding domains. The amino-terminal domain, residues 1 to 107, consists of a five-stranded beta-sheet termed the "wing" domain. Two wing domains ofeach dimer project inward towards the centre of the dodecamer and contribute to dodecamer stabilisation [].Proteins containing this domain include the ornithine decarboxylase, the lysine decarboxylase and the biodegradative arginine decarboxylase. | Short Name: | OKR_de-COase_N |
| DB identifier | Type | Name |
|---|---|---|
| IPR027464 | Domain | Ornithine decarboxylase, N-terminal domain |
