Protein Domain : IPR030282

Type:  Family Name:  Prestin
Description:  Prestin (SLC26A5) belongs to the mammalian SLC26 family of anion transporters []. However, unlike other SLC26 family members with the ability of transporting anions across the cell membrane, prestin primarily functions as a motor protein, and its transport capability is significantly diminished during evolution []. Prestin is a membrane protein responsible for the cellular electromotility of cochlear outer hair cells, which is essential for normal hearing sensitivity [, ]. Prestin senses voltage and binds anions for induction of conformational changes, functioning as a voltage-based molecular motor [, , ]. Short Name:  Prestin

0 Child Features

0 Contains

1 Cross References

Identifier
PTHR11814:SF32

0 Found In

2 GO Annotations

GO Term Gene Name
GO:0007605 IPR030282
GO:0016021 IPR030282

2 Ontology Annotations

GO Term Gene Name
GO:0007605 IPR030282
GO:0016021 IPR030282

1 Parent Features

DB identifier Type Name
IPR001902 Family SLC26A/SulP transporter

0 Proteins

5 Publications

First Author Title Year Journal Volume Pages PubMed ID
            24710176
            18400693
            18195086
            11836512
            24361298