3 Ontology Annotations
| GO Term | Gene Name |
|---|---|
| GO:0042626 | IPR005285 |
| GO:0046618 | IPR005285 |
| GO:0016021 | IPR005285 |
| Type: | Family | Name: | Pleiotropic drug resistance protein PDR/CDR |
| Description: | This family consists of multidrug resistance ATP binding cassette (ABC) transporters from fungi. This family includes PDR10 and PDR15, members of the pleiotropic drug resistance (PDR) network in Saccharomyces cerevisiae [], and CDR transporters from Candida albicans [, , ]. The ABC transporter family is a group of membrane proteins that use the hydrolysis of ATP to power the translocation of a wide variety of substrates across cellular membranes. ABC transporters minimally consist of two conserved regions: a highly conserved nucleotide-binding domain (NBD) and a less conserved transmembrane domain (TMD). Eukaryotic ABC proteins are usually organised either as full transporters (containing two NBDs and two TMDs), or as half transporters (containing one NBD and one TMD), that have to form homo- or heterodimers in order to constitute a functional protein []. | Short Name: | drug-R_PDR/CDR |
| GO Term | Gene Name |
|---|---|
| GO:0042626 | IPR005285 |
| GO:0046618 | IPR005285 |
| GO:0016021 | IPR005285 |
