Protein Domain : IPR029895

Type:  Family Name:  Ectonucleotide pyrophosphatase/phosphodiesterase family member 7
Description:  Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 (ENPP7), also known as alkaline sphingomyelin phosphodiesterase or intestinal alkaline sphingomyelinase, converts sphingomyelin to ceramide in the intestinal tract [, ]. It is also able to inactivate the pro-inflammatory phospholipid PAF (platelet-activating factor) by a phospholipase C activity, and may counteract the development of intestinal inflammation and cancer [, ]. It does not appear to have nucleotide pyrophosphatase activity []. Short Name:  ENPP7

0 Child Features

0 Contains

1 Cross References

Identifier
PTHR10151:SF63

0 Found In

2 GO Annotations

GO Term Gene Name
GO:0004767 IPR029895
GO:0006685 IPR029895

2 Ontology Annotations

GO Term Gene Name
GO:0004767 IPR029895
GO:0006685 IPR029895

1 Parent Features

DB identifier Type Name
IPR024873 Family Ectonucleotide pyrophosphatase/phosphodiesterase family

0 Proteins

5 Publications

First Author Title Year Journal Volume Pages PubMed ID
            12885774
            12671034
            16255717
            18989780
            19598106