Protein Domain : IPR019809

Type:  Conserved_site Name:  Histone H4, conserved site
Description:  Histone H4 is one of the four histones, along with H2A, H2B and H3, which form the eukaryotic nucleosome core. Along with H3, it plays a central role in nucleosome formation. The sequence of histone H4 has remained almost invariant in more then 2 billion years of evolution []. The signature pattern for this entry is a pentapeptide found in positions 14 to 18 of all H4 sequences. It contains a lysine residue which is often acetylated [] and a histidine residue which is implicated in DNA-binding []. Short Name:  Histone_H4_CS
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0 Child Features

0 Contains

1 Cross References

Identifier
PS00047

2 Found Ins

DB identifier Type Name
IPR009072 Domain Histone-fold
IPR001951 Family Histone H4

4 GO Annotations

GO Term Gene Name
GO:0003677 IPR019809
GO:0006334 IPR019809
GO:0000786 IPR019809
GO:0005634 IPR019809

4 Ontology Annotations

GO Term Gene Name
GO:0003677 IPR019809
GO:0006334 IPR019809
GO:0000786 IPR019809
GO:0005634 IPR019809

0 Parent Features

0 Proteins

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            8121801
            6808351
            3340182