| Type: | Family | Name: | Galactokinase, bacterial |
| Description: | Galactokinase catalyses the first reaction in the galactose metabolism pathway, the ATP-dependent phosphorylation of galactose, yielding galactose-1-phosphate [, ].Deficiency in this enzyme results in the disease galactosemia, which is responsible for the formation of cataracts in newborn babies, and is possibly responsible for presenile cataracts inadults []. In yeast, the GAL3 gene product is required for the GAL4-mediated inductionof other enzymes involved in galactose metabolism. The induction of GAL1 production then reinforces this process, increasing the expression of other galactose-inducible genes. GAL3 has been shown tobe similar to the GAL1 protein [].This entry represents bacterial-type galactokinases. | Short Name: | Galactokinase_bac |
