Protein Domain : IPR024304

Type:  Family Name:  Natural killer cell receptor 2B4
Description:  2B4 is a transmembrane receptor which is expressed primarily on natural killer (NK) cells. It plays a role in activating NK-mediated cytotoxicity through its interaction with CD48 on target cells in a subset of CD8 T cells []. The structure of 2B4 consists of an immunoglobulin variable domain fold and contains two beta-sheets. One of the beta-sheets, the six-stranded sheet, contains structural features that may have a role in ligand recognition and receptor function []. Short Name:  NK_rcpt_2B4

0 Child Features

0 Contains

1 Cross References

Identifier
PTHR12080:SF3

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0004872 IPR024304
GO:0005515 IPR024304
GO:0016021 IPR024304

3 Ontology Annotations

GO Term Gene Name
GO:0004872 IPR024304
GO:0005515 IPR024304
GO:0016021 IPR024304

1 Parent Features

DB identifier Type Name
IPR015631 Family Signalling lymphocyte activation molecule family receptors

0 Proteins

1 Publications

First Author Title Year Journal Volume Pages PubMed ID
            15850375