Protein Domain : IPR015588

Type:  Family Name:  Interferon beta
Description:  Interferon beta has many known roles. IFNb has effects on the production of cytokines by T helper lymphocytes, can antagonize some of the proinflammatory effects of IFNgamma, is pro-apoptotic, inhibits the production of matrix metalloproteases, and alters the expression of adhesion molecules and chemokines [].Interferons [] are proteins that produce antiviral and antiproliferative responses in cells. On the basis of their sequence interferons are classified into five groups: alpha, alpha-II (or omega), beta, delta (or trophoblast). The sequence differences may possibly cause different responses to various inducers, or result in the recognition of different target cell types []. The main conserved structural feature of interferons is a disulphide bond that, except in mouse beta interferon, occurs in all alpha, beta and omega sequences. Short Name:  Interferon_beta

0 Child Features

1 Contains

DB identifier Type Name
IPR012351 Domain Four-helical cytokine, core

1 Cross References

Identifier
PTHR11691:SF7

0 Found In

0 GO Annotation

0 Ontology Annotations

1 Parent Features

DB identifier Type Name
IPR000471 Family Interferon alpha/beta/delta

0 Proteins

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            3022999
            6170983
            15264107