Protein Domain : IPR012092

Type:  Family Name:  8-oxoguanine DNA glycosylase/DNA lyase, thermostable
Description:  This entry represents bifunctional, thermostable 8-oxoguanine DNA glycosylase/DNA lyase enzymes (OGG or OG glycosylases), which are involved in base excision repair of DNA damaged by oxidation or by mutagenic agents []. Most damage to bases in DNA is repaired by the base excision repair pathway []. These enzymes have both DNA glycosylase activity () and AP lyase activity (). OGG1 enzymes are active only towards the removal of 8-oxoguanine []. Short Name:  DNA_glyclase/DNA_lyase_thermo
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0 Child Features

1 Contains

DB identifier Type Name
IPR003265 Domain HhH-GPD domain

2 Cross Referencess

Identifier
PIRSF005954
MF_00241

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0003906 IPR012092
GO:0016799 IPR012092
GO:0006281 IPR012092

3 Ontology Annotations

GO Term Gene Name
GO:0003906 IPR012092
GO:0016799 IPR012092
GO:0006281 IPR012092

0 Parent Features

0 Proteins

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            10521423
            15588838
            14503888