3 Ontology Annotations
| GO Term | Gene Name |
|---|---|
| GO:0005179 | IPR000065 |
| GO:0007165 | IPR000065 |
| GO:0005576 | IPR000065 |
| Type: | Family | Name: | Leptin |
| Description: | Leptin, a metabolic monitor of food intake and energy need, is expressed by the ob obesity gene. The protein may function as part of a signallingpathway from adipose tissue that acts to regulate the size of the body fat depot [], the hormone effectively turning the brain's appetitemessage off when it senses that the body is satiated. Obese humans have high levels of the protein, suggesting a similarity to type II (adultonset) diabetes, in which sufferers over-produce insulin, but can't respond to it metabolically - they have become insulin resistant. Similarly, it isthought that obese individuals may be leptin resistant. | Short Name: | Leptin |
| GO Term | Gene Name |
|---|---|
| GO:0005179 | IPR000065 |
| GO:0007165 | IPR000065 |
| GO:0005576 | IPR000065 |
