3 Ontology Annotations
GO Term | Gene Name |
---|---|
GO:0005248 | IPR028808 |
GO:0006814 | IPR028808 |
GO:0001518 | IPR028808 |
1 Parent Features
DB identifier | Type | Name |
---|---|---|
IPR001696 | Family | Voltage gated sodium channel, alpha subunit |
Type: | Family | Name: | Voltage gated sodium channel, alpha-3 subunit |
Description: | Nine voltage-gated sodium channels (Navs) are expressed in complex patterns in mammalian nerve and muscle. These channels mediate the influx of Na+ ions in response to local depolarising stimuli. Nav channels are composed of a pore-forming alpha-subunit associated with one or more auxiliary beta-subunits. The pore-forming alpha subunit is sufficient for functional expression, but the localisation, kinetics and voltage dependence of channel gating are modified by the beta subunits [, ].This entry represents Nav1.3 (sodium channel protein type 3 subunit alpha). It plays an important role in neuropathic pain []. | Short Name: | Na_channel_a3su |
GO Term | Gene Name |
---|---|
GO:0005248 | IPR028808 |
GO:0006814 | IPR028808 |
GO:0001518 | IPR028808 |
DB identifier | Type | Name |
---|---|---|
IPR001696 | Family | Voltage gated sodium channel, alpha subunit |