Type: | Family | Name: | Squalene synthase HpnC |
Description: | Proteins in this entry are members of a superfamily of phytoene and squalene synthases which catalyse the head-to-head condensation of polyisoprene pyrophosphates. They are often encoded in the same genetic locus as squalene-hopene cyclase genes, and are never associated with genes for the metabolism of phytoene. In the organisms Zymomonas mobilisand Bradyrhizobium japonicumthey have been characterised as squalene synthases (farnesyl-pyrophosphate ligases) []. HpnC is often encoded in tandem with the gene for HpnD, which appears to have resulted from an ancient gene duplication event. Presumably these proteins form a heteromeric complex, but this has not yet been experimentally demonstrated. | Short Name: | Squalene_synthase_HpnC |