Protein Domain : IPR011872

Type:  Family Name:  Homocitrate synthase, fungi/archaea
Description:  This entry includes the yeast LYS21 gene which carries out the first step of the alpha-aminoadipate (AAA) lysine biosynthesis pathway [, ]. A related pathway is found in Thermus thermophilus[]. This enzyme is closely related to 2-isopropylmalate synthase (LeuA) and citramalate synthase (CimA), both of which are present in the euryarchaeota. Some archaea have a separate homocitrate synthase (AksA) which also synthesizes longer homocitrate analogs []. Short Name:  Homocitrate_synth_fun/arc
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0 Child Features

1 Contains

DB identifier Type Name
IPR002034 Conserved_site Alpha-isopropylmalate/homocitrate synthase, conserved site

1 Cross References

Identifier
TIGR02146

0 Found In

4 GO Annotations

GO Term Gene Name
GO:0004410 IPR011872
GO:0046912 IPR011872
GO:0019752 IPR011872
GO:0019878 IPR011872

4 Ontology Annotations

GO Term Gene Name
GO:0004410 IPR011872
GO:0046912 IPR011872
GO:0019752 IPR011872
GO:0019878 IPR011872

0 Parent Features

0 Proteins

4 Publications

First Author Title Year Journal Volume Pages PubMed ID
            10613839
            9665716
            16299000
            9099739