Protein Domain : IPR030370

Type:  Family Name:  ATP-binding cassette subfamily A member 9
Description:  Members of ABC (ATP-binding cassette) transporter subfamily A are full-length transporters [], which consist of a single long polypeptide chain organised into two tandemly arranged halves. Each half contains a membrane-spanning domain (MSD) followed by a cytoplasmic nucleotide binding domain (NBD) []. Human ABCA9 mRNA is induced during the differentiation of monocytes into macrophages and suppressed by cholesterol import, indicating that it is a cholesterol-responsive gene. ABCA9 is therefore likely to be involved in monocyte differentiation and macrophage lipid homeostasis []. Short Name:  ABCA9
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0 Child Features

0 Contains

1 Cross References

Identifier
PTHR19229:SF11

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0005215 IPR030370
GO:0006810 IPR030370
GO:0016021 IPR030370

3 Ontology Annotations

GO Term Gene Name
GO:0005215 IPR030370
GO:0006810 IPR030370
GO:0016021 IPR030370

1 Parent Features

DB identifier Type Name
IPR026082 Family ABC transporter A, ABCA

0 Proteins

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            11320094
            12150964
            23103747