Protein Domain : IPR030366

Type:  Family Name:  ATP-binding cassette subfamily A member 2
Description:  ATP-binding cassette subfamily A member 2 (ABCA2) belongs to the ABC transporter family, whose remembers are full-length transporters organised in two tandem halves, each with a hydrophobic TMD followed by a cytoplasmic NBD [].ABCA2 is mainly expressed in the central nervous system, ovary and macrophages [, ]. It may modulate cholesterol homeostasis in neuronal cells []. It may regulate esterification of plasma membrane cholesterol by modulation of sphingolipid metabolism []. Short Name:  ABCA2

0 Child Features

0 Contains

1 Cross References

Identifier
PTHR19229:SF116

0 Found In

2 GO Annotations

GO Term Gene Name
GO:0006810 IPR030366
GO:0016021 IPR030366

2 Ontology Annotations

GO Term Gene Name
GO:0006810 IPR030366
GO:0016021 IPR030366

1 Parent Features

DB identifier Type Name
IPR026082 Family ABC transporter A, ABCA

0 Proteins

4 Publications

First Author Title Year Journal Volume Pages PubMed ID
            23103747
            19429473
            21810484
            24201375