3 Ontology Annotations
GO Term | Gene Name |
---|---|
GO:0004674 | IPR016238 |
GO:0006468 | IPR016238 |
GO:0007165 | IPR016238 |
Type: | Family | Name: | Ribosomal protein S6 kinase |
Description: | This entry represents ribosomal protein S6 kinase. S6 kinase is part of the mammalian target of rapamycin (mTOR) pathway, which is a key regulator of cell growth via the regulation of protein synthesis. Both S6 kinase and eukaryotic initiation factor 4E-binding protein 1 (4EBP-1) are key mTOR effectors of cell growth []. S6 kinase specifically phosphorylates ribosomal protein S6 in response to insulin or several classes of mitogens. S6 kinase is activated by serine/threonine phosphorylation and protein kinase C, and is inactivated by type 2A phosphatase []. S6 kinase interacts with PPP1R9A/neurabin-1 []. | Short Name: | Ribosomal_S6_kinase |
GO Term | Gene Name |
---|---|
GO:0004674 | IPR016238 |
GO:0006468 | IPR016238 |
GO:0007165 | IPR016238 |