Protein Domain : IPR004189

Type:  Domain Name:  Bacteriophage Mu, transposase
Description:  This transposase is essential for integration, replication-transposition and excision of Bacteriophage MuDNA. Transposition requires transposase and a transposition enhancer, and the DNA can be transposed into multiple sites in bacterial genomes.The crystal structure of the core domain of Mu transposase, MuA, has been determined. The first of two subdomains contains the active site and, despite very limited sequence homology, exhibits a striking similarity to the core domain of Human immunodeficiency virus 1integrase. The enzymatic activity of MuA is known to be activated by formation of a DNA-bound tetramer of the protein []. Short Name:  Phage_Mu_transposase
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0 Child Features

0 Contains

1 Cross References

Identifier
PF02914

0 Found In

4 GO Annotations

GO Term Gene Name
GO:0003677 IPR004189
GO:0004803 IPR004189
GO:0006313 IPR004189
GO:0015074 IPR004189

4 Ontology Annotations

GO Term Gene Name
GO:0003677 IPR004189
GO:0004803 IPR004189
GO:0006313 IPR004189
GO:0015074 IPR004189

1 Parent Features

DB identifier Type Name
IPR012337 Domain Ribonuclease H-like domain

0 Proteins

1 Publications

First Author Title Year Journal Volume Pages PubMed ID
            7628012