| Type: | PTM | Name: | EGF-type aspartate/asparagine hydroxylation site |
| Description: | Post-translational hydroxylation of aspartic acid or asparagine [] to formerythro-beta-hydroxyaspartic acid or erythro-beta-hydroxyasparagine has been identified in a number of proteins with domains homologous to epidermal growthfactor (EGF). Examples of such proteins are the blood coagulation protein factors VII, IX and X, proteins C, S, and Z, the LDL receptor, thrombomodulin,etc. Based on sequence comparisons of the EGF-homology region that contains hydroxylated Asp or Asn, a consensus sequence has been identified that seemsto be required by the hydroxylase(s). | Short Name: | EGF-type_Asp/Asn_hydroxyl_site |
| DB identifier | Type | Name |
|---|---|---|
| IPR000742 | Domain | EGF-like domain |
| IPR001881 | Domain | EGF-like calcium-binding domain |
| IPR016317 | Family | Pro-epidermal growth factor |
| IPR016316 | Family | Thrombomodulin |
| IPR008297 | Family | Notch |
| IPR003056 | Family | GPCR, family 2, CD97 antigen |
| IPR017048 | Family | Fibulin-1 |
| IPR011398 | Family | Fibrillin |
| IPR015446 | Family | Bone morphogenetic protein 1/tolloid-like protein |
