Protein Domain : IPR016302

Type:  Family Name:  Anthranilate synthase component 2
Description:  This entry represents a trifunctional tryptophan biosynthesis protein found in some yeast. In Neurospora crassa the anthranilate synthase complex catalyses the first, third and fourth enzymatic reactions of the committed pathway of tryptophan biosynthesis. This heterotetrameric complex (alpa2/beta2) is composed of a monofunctional alpha-subunit or component I (the trp-2 gene product), which catalyses the formation of anthranilate using ammonia rather than glutamine, and a beta-subunit or component II (the trp-1 gene product), which is a trifunctional polypeptide bearing the glutamine amidotransferase (TrpG), indole-3-glycerol-phosphate synthase (TrpC), and phosphoribosylanthranilate isomerase (TrpF) activities [, ]. Short Name:  Anthranilate_synth_II

0 Child Features

4 Contains

DB identifier Type Name
IPR013785 Domain Aldolase-type TIM barrel
IPR011060 Domain Ribulose-phosphate binding barrel
IPR013798 Domain Indole-3-glycerol phosphate synthase
IPR001468 Conserved_site Indole-3-glycerol phosphate synthase, conserved site

1 Cross References

Identifier
PIRSF001382

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0004049 IPR016302
GO:0004425 IPR016302
GO:0004640 IPR016302

3 Ontology Annotations

GO Term Gene Name
GO:0004049 IPR016302
GO:0004425 IPR016302
GO:0004640 IPR016302

0 Parent Features

0 Proteins

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            6221060
            2147978