| Type: | Family | Name: | Transcription elongation factor Spt5, archaeal |
| Description: | Transcription elongation factor Spt5 is composed of a NusG N-terminal (NGN) domain and a KOW domain, similar to bacterial NusG []. It forms heterodimer with Spt4 and stimulates transcription elongation []. Its NGN domain closes the RNAP active centre cleft to lock nucleic acids and render the elongation complex stable and processive []. Its KOW domain may interact with RNA and/or other factors []. The structure of Spt4/5 complex has been solved []. | Short Name: | Spt5_arc |
