Protein Domain : IPR020921

Type:  Family Name:  Erythronate-4-phosphate dehydrogenase
Description:  Pyridoxal-5'-phosphate is the active form of vitamin B6 and is an essential cofactor for many enzymes, particularly those involved in amino acid metabolism []. There are three known pathways for pyridoxal-5'-phosphate biosynthesis: the de novo pathway, the salvage pathway, and the fungal type pathway. Bacteria, fungi, parasites and plants all possess at least one of these pathways, but higher organisms, such as insects and mammals, are incapable of synthesising this compound and need vitamin B6 in their diet to survive.Erythronate-4-phosphate dehydrogenase catalyses the first step in the de novo biosynthetic pathway, the oxidation of erythrose-4-phosphate to 4-phosphoerythronate []. Short Name:  Erythronate-4-P_DHase
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0 Child Features

2 Contains

DB identifier Type Name
IPR016040 Domain NAD(P)-binding domain
IPR006140 Domain D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain

1 Cross References

Identifier
MF_01825

0 Found In

4 GO Annotations

GO Term Gene Name
GO:0033711 IPR020921
GO:0008615 IPR020921
GO:0055114 IPR020921
GO:0005737 IPR020921

4 Ontology Annotations

GO Term Gene Name
GO:0033711 IPR020921
GO:0008615 IPR020921
GO:0055114 IPR020921
GO:0005737 IPR020921

0 Parent Features

0 Proteins

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            15483325
            9696782