Protein Domain : IPR018359

Type:  Conserved_site Name:  Bromodomain, conserved site
Description:  Bromodomains are found in a variety of mammalian, invertebrate and yeast DNA-binding proteins []. Bromodomains can interact withacetylated lysine [].In some proteins, the classical bromodomain has diverged to such an extent that parts of the region are either missing or contain an insertion(e.g., mammalian protein HRX, Caenorhabditis eleganshypothetical protein ZK783.4, yeast protein YTA7). The bromodomain may occur as a single copy, or in duplicate.The precise function of the domain is unclear, but it may be involved in protein-protein interactions and may play a role in assembly or activityof multi-component complexes involved in transcriptional activation []. Short Name:  Bromodomain_CS

0 Child Features

0 Contains

1 Cross References

Identifier
PS00633

4 Found Ins

DB identifier Type Name
IPR001487 Domain Bromodomain
IPR017413 Family Transcription factor GTE1/GTE6
IPR016376 Family Histone acetylase PCAF
IPR011177 Family Transcription initiation factor TFIID subunit 1, animal

0 GO Annotation

0 Ontology Annotations

0 Parent Features

0 Proteins

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            7580139
            1350857
            9175470