GO Term : GO:0004421 hydroxymethylglutaryl-CoA synthase activity GO

Namespace:  molecular_function Obsolete:  false
description  Catalysis of the reaction: acetoacetyl-CoA + acetyl-CoA + H(2)O = (S)-3-hydroxy-3-methylglutaryl-CoA + CoA + H(+).

0 Cross References

1 Data Sets

Name URL
InterPro domain GO annotations  

1 Ontology

Name
GO

10158 Ontology Annotations

Class GO Term Gene Name Db
GOAnnotation GO:0004421 179152  
OntologyAnnotation GO:0004421 179152 GO
GOAnnotation GO:0004421 121372  
OntologyAnnotation GO:0004421 121372 GO
GOAnnotation GO:0004421 evm.TU.supercontig_29.22  
OntologyAnnotation GO:0004421 evm.model.supercontig_29.22 GO
GOAnnotation GO:0004421 30190.t000345  
OntologyAnnotation GO:0004421 30190.m011109 GO
GOAnnotation GO:0004421 40953.t000001  
OntologyAnnotation GO:0004421 40953.m000013 GO
GOAnnotation GO:0004421 55320.t000001  
OntologyAnnotation GO:0004421 55320.m000010 GO
GOAnnotation GO:0004421 Cucsa.320170  
OntologyAnnotation GO:0004421 Cucsa.320170.1 GO
GOAnnotation GO:0004421 orange1.1g012353m.g  
OntologyAnnotation GO:0004421 orange1.1g023511m GO
OntologyAnnotation GO:0004421 orange1.1g021936m GO
OntologyAnnotation GO:0004421 orange1.1g018515m GO
OntologyAnnotation GO:0004421 orange1.1g013297m GO
OntologyAnnotation GO:0004421 orange1.1g012353m GO
OntologyAnnotation GO:0004421 orange1.1g012273m GO
OntologyAnnotation GO:0004421 orange1.1g012253m GO
GOAnnotation GO:0004421 orange1.1g012253m.g  
OntologyAnnotation GO:0004421 orange1.1g023575m GO
OntologyAnnotation GO:0004421 orange1.1g018518m GO
OntologyAnnotation GO:0004421 orange1.1g012909m GO
GOAnnotation GO:0004421 AT4G11820  
OntologyAnnotation GO:0004421 AT4G11820.2 GO
OntologyAnnotation GO:0004421 AT4G11820.1 GO
GOAnnotation GO:0004421 Thhalv10028643m.g  

8 Parents

Identifier Name Description
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0016746 transferase activity, transferring acyl groups Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor).
GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor), with the acyl group being converted into alkyl on transfer.
GO:0016740 transferase activity Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.
GO:0004421 hydroxymethylglutaryl-CoA synthase activity Catalysis of the reaction: acetoacetyl-CoA + acetyl-CoA + H(2)O = (S)-3-hydroxy-3-methylglutaryl-CoA + CoA + H(+).
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.

7 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0046912 GO:0004421
is_a GO:0003674 GO:0004421
is_a GO:0016740 GO:0004421
part of GO:0008150 GO:0004421
is_a GO:0016746 GO:0004421
part of GO:0008152 GO:0004421
is_a GO:0003824 GO:0004421

14 Synonyms

Name Type
(S)-3-hydroxy-3-methylglutaryl-CoA acetoacetyl-CoA-lyase (CoA-acetylating) synonym
(s)-3-hydroxy-3-methylglutaryl-CoA acetoacetyl-CoA-lyase (CoA- acetylating) activity synonym
3-hydroxy-3-methylglutaryl coenzyme A synthase activity synonym
3-hydroxy-3-methylglutaryl CoA synthetase activity synonym
3-hydroxy-3-methylglutaryl-CoA synthase activity synonym
3-hydroxy-3-methylglutaryl coenzyme A synthetase activity synonym
acetoacetyl coenzyme A transacetase activity synonym
3-hydroxy-3-methylglutaryl-coenzyme A synthase activity synonym
beta-hydroxy-beta-methylglutaryl-CoA synthase activity synonym
acetyl-CoA:acetoacetyl-CoA C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming) synonym
hydroxymethylglutaryl coenzyme A synthase activity synonym
HMG-CoA synthase activity synonym
hydroxymethylglutaryl coenzyme alpha-condensing enzyme activity synonym
hydroxymethylglutaryl coenzyme A-condensing enzyme synonym