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GO:0003824
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catalytic activity
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Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. |
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GO:0016491
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oxidoreductase activity
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Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced. |
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GO:0055114
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oxidation-reduction process
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A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons. |
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GO:0005515
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protein binding
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Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). |
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GO:0006979
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response to oxidative stress
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Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals. |
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GO:0005488
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binding
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The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule. |
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GO:0016209
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antioxidant activity
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Inhibition of the reactions brought about by dioxygen (O2) or peroxides. Usually the antioxidant is effective because it can itself be more easily oxidized than the substance protected. The term is often applied to components that can trap free radicals, thereby breaking the chain reaction that normally leads to extensive biological damage. |
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GO:0008152
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metabolic process
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The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation. |
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GO:0046872
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metal ion binding
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Interacting selectively and non-covalently with any metal ion. |
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GO:0005507
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copper ion binding
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Interacting selectively and non-covalently with copper (Cu) ions. |
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GO:0044237
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cellular metabolic process
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The chemical reactions and pathways by which individual cells transform chemical substances. |
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GO:0043169
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cation binding
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Interacting selectively and non-covalently with cations, charged atoms or groups of atoms with a net positive charge. |
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GO:0006950
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response to stress
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Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). |
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GO:0030234
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enzyme regulator activity
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Binds to and modulates the activity of an enzyme. |
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GO:0019430
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removal of superoxide radicals
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Any process, acting at the cellular level, involved in removing superoxide radicals (O2-) from a cell or organism, e.g. by conversion to dioxygen (O2) and hydrogen peroxide (H2O2). |
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GO:0004784
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superoxide dismutase activity
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Catalysis of the reaction: 2 superoxide + 2 H+ = O2 + hydrogen peroxide. |
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GO:0006801
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superoxide metabolic process
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The chemical reactions and pathways involving superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species. |
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GO:0046914
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transition metal ion binding
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Interacting selectively and non-covalently with a transition metal ions; a transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver. |
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GO:0016531
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copper chaperone activity
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Assists in the delivery of copper ions to target proteins or compartments. |
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GO:0043085
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positive regulation of catalytic activity
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Any process that activates or increases the activity of an enzyme. |
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GO:0016532
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superoxide dismutase copper chaperone activity
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A copper chaperone activity that specifically delivers copper to the Cu-Zn superoxide dismutase, to activate superoxide dismutase activity. |
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GO:0050790
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regulation of catalytic activity
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Any process that modulates the activity of an enzyme. |
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GO:0034599
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cellular response to oxidative stress
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Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals. |
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GO:0051716
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cellular response to stimulus
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Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell. |
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GO:0009636
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response to toxic substance
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Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus. |
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GO:0008047
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enzyme activator activity
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Binds to and increases the activity of an enzyme. |
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GO:0009987
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cellular process
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Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. |
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GO:0043167
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ion binding
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Interacting selectively and non-covalently with ions, charged atoms or groups of atoms. |
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GO:0000302
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response to reactive oxygen species
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Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals. |
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GO:0098869
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cellular oxidant detoxification
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Any process carried out at the cellular level that reduces or removes the toxicity superoxide radicals or hydrogen peroxide. |
