GO Term : GO:0003852 2-isopropylmalate synthase activity GO

Namespace:  molecular_function Obsolete:  false
description  Catalysis of the reaction: 3-methyl-2-oxobutanoate + acetyl-CoA + H(2)O = (2S)-2-isopropylmalate + CoA + H(+).

0 Cross References

1 Data Sets

Name URL
InterPro domain GO annotations  

1 Ontology

Name
GO

10158 Ontology Annotations

Class GO Term Gene Name Db
GOAnnotation GO:0003852 111991  
OntologyAnnotation GO:0003852 111991 GO
GOAnnotation GO:0003852 97271  
OntologyAnnotation GO:0003852 97271 GO
OntologyAnnotation GO:0003852 evm.model.supercontig_71.35 GO
GOAnnotation GO:0003852 evm.TU.supercontig_71.35  
GOAnnotation GO:0003852 30041.t000010  
OntologyAnnotation GO:0003852 30041.m000240 GO
GOAnnotation GO:0003852 34620.t000002  
OntologyAnnotation GO:0003852 34620.m000030 GO
OntologyAnnotation GO:0003852 Cucsa.012740.1 GO
OntologyAnnotation GO:0003852 Cucsa.012740.2 GO
OntologyAnnotation GO:0003852 Cucsa.012740.3 GO
GOAnnotation GO:0003852 Cucsa.012740  
OntologyAnnotation GO:0003852 orange1.1g006969m GO
GOAnnotation GO:0003852 orange1.1g006969m.g  
OntologyAnnotation GO:0003852 orange1.1g007056m GO
GOAnnotation GO:0003852 AT1G18500  
OntologyAnnotation GO:0003852 AT1G18500.1 GO
OntologyAnnotation GO:0003852 AT1G74040.1 GO
GOAnnotation GO:0003852 AT1G74040  
GOAnnotation GO:0003852 Thhalv10007073m.g  
OntologyAnnotation GO:0003852 Thhalv10007073m GO
GOAnnotation GO:0003852 Thhalv10018267m.g  
OntologyAnnotation GO:0003852 Thhalv10018267m GO
GOAnnotation GO:0003852 Ciclev10020218m.g  
OntologyAnnotation GO:0003852 Ciclev10020218m GO
GOAnnotation GO:0003852 Lus10019574.g  
OntologyAnnotation GO:0003852 Lus10019574 GO
OntologyAnnotation GO:0003852 Potri.005G083100.3 GO

8 Parents

Identifier Name Description
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0016746 transferase activity, transferring acyl groups Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor).
GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor), with the acyl group being converted into alkyl on transfer.
GO:0016740 transferase activity Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.
GO:0003852 2-isopropylmalate synthase activity Catalysis of the reaction: 3-methyl-2-oxobutanoate + acetyl-CoA + H(2)O = (2S)-2-isopropylmalate + CoA + H(+).
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.

7 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0046912 GO:0003852
is_a GO:0003674 GO:0003852
part of GO:0008150 GO:0003852
is_a GO:0016740 GO:0003852
part of GO:0008152 GO:0003852
is_a GO:0016746 GO:0003852
is_a GO:0003824 GO:0003852

8 Synonyms

Name Type
isopropylmalate synthetase activity synonym
3-carboxy-3-hydroxy-4-methylpentanoate 3-methyl-2-oxobutanoate-lyase (CoA-acetylating) activity synonym
acetyl-CoA:3-methyl-2-oxobutanoate C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming) synonym
alpha-IPM synthetase activity synonym
alpha-isopropylmalate synthase activity synonym
alpha-isopropylmalate synthetase activity synonym
alpha-isopropylmalic synthetase activity synonym
isopropylmalate synthase activity synonym