GO Term : GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway GO
Namespace:  biological_process Obsolete:  false
description  The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, where the pathway proceeds with activation of protein kinase C (PKC). PKC is activated by second messengers including diacylglycerol (DAG).
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0 Cross References

1 Data Sets

Name URL
InterPro domain GO annotations  

1 Ontology

Name
GO

10158 Ontology Annotations

Class GO Term Gene Name Db
GOAnnotation GO:0007205 110542  
OntologyAnnotation GO:0007205 110542 GO
OntologyAnnotation GO:0007205 439175 GO
GOAnnotation GO:0007205 439175  
GOAnnotation GO:0007205 115839  
OntologyAnnotation GO:0007205 115839 GO
GOAnnotation GO:0007205 90522  
OntologyAnnotation GO:0007205 90522 GO
OntologyAnnotation GO:0007205 evm.model.supercontig_12.23 GO
GOAnnotation GO:0007205 evm.TU.supercontig_12.23  
OntologyAnnotation GO:0007205 evm.model.supercontig_34.77 GO
GOAnnotation GO:0007205 evm.TU.supercontig_34.77  
OntologyAnnotation GO:0007205 evm.model.supercontig_34.78 GO
GOAnnotation GO:0007205 evm.TU.supercontig_34.78  
GOAnnotation GO:0007205 evm.TU.supercontig_3663.1  
OntologyAnnotation GO:0007205 evm.model.supercontig_3663.1 GO
OntologyAnnotation GO:0007205 evm.model.supercontig_37.51 GO
GOAnnotation GO:0007205 evm.TU.supercontig_37.51  
OntologyAnnotation GO:0007205 evm.model.supercontig_450.4 GO
GOAnnotation GO:0007205 evm.TU.supercontig_450.4  
GOAnnotation GO:0007205 evm.TU.supercontig_94.22  
OntologyAnnotation GO:0007205 evm.model.supercontig_94.22 GO
GOAnnotation GO:0007205 29749.t000004  
OntologyAnnotation GO:0007205 29749.m000143 GO
GOAnnotation GO:0007205 29983.t000178  
OntologyAnnotation GO:0007205 29983.m003279 GO
GOAnnotation GO:0007205 30027.t000027  
OntologyAnnotation GO:0007205 30027.m000834 GO
GOAnnotation GO:0007205 30138.t000176  
OntologyAnnotation GO:0007205 30138.m004002 GO

50 Parents

Identifier Name Description
GO:0007165 signal transduction The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
GO:0007186 G-protein coupled receptor signaling pathway A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. The pathway can start from the plasma membrane, Golgi or nuclear membrane (PMID:24568158 and PMID:16902576).
GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, where the pathway proceeds with activation of protein kinase C (PKC). PKC is activated by second messengers including diacylglycerol (DAG).
GO:0043085 positive regulation of catalytic activity Any process that activates or increases the activity of an enzyme.
GO:0001932 regulation of protein phosphorylation Any process that modulates the frequency, rate or extent of addition of phosphate groups into an amino acid in a protein.
GO:0032147 activation of protein kinase activity Any process that initiates the activity of an inactive protein kinase.
GO:0050790 regulation of catalytic activity Any process that modulates the activity of an enzyme.
GO:0045859 regulation of protein kinase activity Any process that modulates the frequency, rate or extent of protein kinase activity.
GO:0051716 cellular response to stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell.
GO:0042325 regulation of phosphorylation Any process that modulates the frequency, rate or extent of addition of phosphate groups into a molecule.
GO:0007154 cell communication Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0033674 positive regulation of kinase activity Any process that activates or increases the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
GO:0044763 single-organism cellular process Any process that is carried out at the cellular level, occurring within a single organism.
GO:0044699 single-organism process A biological process that involves only one organism.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.
GO:0065007 biological regulation Any process that modulates a measurable attribute of any biological process, quality or function.
GO:0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0080090 regulation of primary metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism involving those compounds formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
GO:0031323 regulation of cellular metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.
GO:0050789 regulation of biological process Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.
GO:0060255 regulation of macromolecule metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0043549 regulation of kinase activity Any process that modulates the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
GO:0051246 regulation of protein metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein.
GO:0031399 regulation of protein modification process Any process that modulates the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein.
GO:0051338 regulation of transferase activity Any process that modulates the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.
GO:0051174 regulation of phosphorus metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus.
GO:0019220 regulation of phosphate metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphates.

56 Relations

Relationship
Parent Term . Identifier
Child Term . Identifier
is_a GO:0007186 GO:0007205
has_part GO:1990051 GO:0007205
has_part GO:0043549 GO:0007205
has_part GO:0080090 GO:0007205
has_part GO:0031323 GO:0007205
has_part GO:0031401 GO:0007205
part of GO:0050896 GO:0007205
has_part GO:0031325 GO:0007205
has_part GO:0048522 GO:0007205
is_a GO:0050789 GO:0007205
regulates GO:0009987 GO:0007205
part of GO:0007154 GO:0007205
part of GO:0044763 GO:0007205
has_part GO:0051174 GO:0007205
is_a GO:0008150 GO:0007205
has_part GO:0045859 GO:0007205
has_part GO:0045937 GO:0007205
has_part GO:0042327 GO:0007205
has_part GO:0008150 GO:0007205
regulates GO:0008150 GO:0007205
has_part GO:0042325 GO:0007205
is_a GO:0065007 GO:0007205
has_part GO:0060255 GO:0007205
has_part GO:0031399 GO:0007205
has_part GO:0051338 GO:0007205
part of GO:0008150 GO:0007205
is_a GO:0050794 GO:0007205
has_part GO:0051347 GO:0007205
has_part GO:0045860 GO:0007205
part of GO:0044699 GO:0007205

2 Synonyms

Name Type
activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway synonym
activation of protein kinase C activity by G-protein coupled receptor protein signalling pathway synonym