GO Term : GO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity GO

Namespace:  molecular_function Obsolete:  false
description  Catalysis of the reaction: (S)-malate + NAD+ = pyruvate + CO2 + NADH + H+.

0 Cross References

1 Data Sets

Name URL
InterPro domain GO annotations  

1 Ontology

Name
GO

10158 Ontology Annotations

Class GO Term Gene Name Db
GOAnnotation GO:0004471 130484  
OntologyAnnotation GO:0004471 130484 GO
OntologyAnnotation GO:0004471 428353 GO
GOAnnotation GO:0004471 428353  
OntologyAnnotation GO:0004471 431097 GO
GOAnnotation GO:0004471 431097  
GOAnnotation GO:0004471 142026  
OntologyAnnotation GO:0004471 142026 GO
GOAnnotation GO:0004471 176472  
OntologyAnnotation GO:0004471 176472 GO
GOAnnotation GO:0004471 evm.TU.contig_43450  
OntologyAnnotation GO:0004471 evm.TU.contig_43450.1 GO
GOAnnotation GO:0004471 evm.TU.supercontig_18.186  
OntologyAnnotation GO:0004471 evm.model.supercontig_18.186 GO
OntologyAnnotation GO:0004471 evm.model.supercontig_25.2 GO
GOAnnotation GO:0004471 evm.TU.supercontig_25.2  
OntologyAnnotation GO:0004471 evm.model.supercontig_40.72 GO
GOAnnotation GO:0004471 evm.TU.supercontig_40.72  
OntologyAnnotation GO:0004471 evm.model.supercontig_52.65 GO
GOAnnotation GO:0004471 evm.TU.supercontig_52.65  
GOAnnotation GO:0004471 evm.TU.supercontig_7.207  
OntologyAnnotation GO:0004471 evm.model.supercontig_7.207 GO
OntologyAnnotation GO:0004471 29709.m001210 GO
GOAnnotation GO:0004471 29709.t000046  
OntologyAnnotation GO:0004471 29794.m003406 GO
GOAnnotation GO:0004471 29794.t000105  
OntologyAnnotation GO:0004471 29912.m005447 GO
GOAnnotation GO:0004471 29912.t000173  
GOAnnotation GO:0004471 30146.t000087  
OntologyAnnotation GO:0004471 30146.m003510 GO

13 Parents

Identifier Name Description
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016491 oxidoreductase activity Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
GO:0016614 oxidoreductase activity, acting on CH-OH group of donors Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group act as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
GO:0055114 oxidation-reduction process A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP.
GO:0016615 malate dehydrogenase activity Catalysis of the reversible conversion of pyruvate or oxaloacetate to malate.
GO:0004470 malic enzyme activity Catalysis of the oxidative decarboxylation of malate with the concomitant production of pyruvate.
GO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity Catalysis of the reaction: (S)-malate + NAD+ = pyruvate + CO2 + NADH + H+.
GO:0044699 single-organism process A biological process that involves only one organism.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0044710 single-organism metabolic process A metabolic process - chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances - which involves a single organism.

12 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0016616 GO:0004471
is_a GO:0004470 GO:0004471
is_a GO:0016614 GO:0004471
is_a GO:0016615 GO:0004471
is_a GO:0016491 GO:0004471
is_a GO:0003824 GO:0004471
part of GO:0044710 GO:0004471
part of GO:0044699 GO:0004471
part of GO:0055114 GO:0004471
is_a GO:0003674 GO:0004471
part of GO:0008150 GO:0004471
part of GO:0008152 GO:0004471

10 Synonyms

Name Type
(S)-malate:NAD+ oxidoreductase (decarboxylating) synonym
malate dehydrogenase (decarboxylating) activity synonym
(S)-malate:NAD+ oxidoreductase (oxaloacetate-decarboxylating) synonym
'malic' enzyme synonym
NAD-linked malic enzyme synonym
malate dehydrogenase (oxaloacetate-decarboxylating) activity synonym
NAD-specific malic enzyme synonym
NAD-malic enzyme activity synonym
GO:0016619 alt_id
GO:0004472 alt_id