GO Term : GO:0008236 serine-type peptidase activity GO

Namespace:  molecular_function Obsolete:  false
description  Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).

0 Cross References

1 Data Sets

Name URL
InterPro domain GO annotations  

1 Ontology

Name
GO

10158 Ontology Annotations

Class GO Term Gene Name Db
GOAnnotation GO:0008236 419277  
OntologyAnnotation GO:0008236 419277 GO
GOAnnotation GO:0008236 111339  
OntologyAnnotation GO:0008236 111339 GO
OntologyAnnotation GO:0008236 111680 GO
GOAnnotation GO:0008236 111680  
GOAnnotation GO:0008236 419387  
OntologyAnnotation GO:0008236 419387 GO
OntologyAnnotation GO:0008236 112098 GO
GOAnnotation GO:0008236 112098  
GOAnnotation GO:0008236 420257  
OntologyAnnotation GO:0008236 420257 GO
GOAnnotation GO:0008236 154815  
OntologyAnnotation GO:0008236 154815 GO
OntologyAnnotation GO:0008236 58024 GO
GOAnnotation GO:0008236 58024  
GOAnnotation GO:0008236 143443  
OntologyAnnotation GO:0008236 143443 GO
GOAnnotation GO:0008236 121429  
OntologyAnnotation GO:0008236 121429 GO
GOAnnotation GO:0008236 122204  
OntologyAnnotation GO:0008236 122204 GO
GOAnnotation GO:0008236 424499  
OntologyAnnotation GO:0008236 424499 GO
OntologyAnnotation GO:0008236 85448 GO
GOAnnotation GO:0008236 85448  
GOAnnotation GO:0008236 86052  
OntologyAnnotation GO:0008236 86052 GO
GOAnnotation GO:0008236 18112  
OntologyAnnotation GO:0008236 18112 GO

14 Parents

Identifier Name Description
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016787 hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.
GO:0006508 proteolysis The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0008233 peptidase activity Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.
GO:0019538 protein metabolic process The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification.
GO:0008236 serine-type peptidase activity Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).
GO:0070011 peptidase activity, acting on L-amino acid peptides Catalysis of the hydrolysis of peptide bonds formed between L-amino acids.
GO:0071704 organic substance metabolic process The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon.
GO:0044238 primary metabolic process The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0043170 macromolecule metabolic process The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0017171 serine hydrolase activity Catalysis of the hydrolysis of a substrate by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).

34 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0008236 GO:0004185
is_a GO:0008236 GO:0004252
negatively regulates GO:0008236 GO:0004867
is_a GO:0070011 GO:0008236
is_a GO:0017171 GO:0008236
part of GO:0008152 GO:0008236
part of GO:0006508 GO:0008236
part of GO:0008150 GO:0008236
is_a GO:0003674 GO:0008236
is_a GO:0016787 GO:0008236
part of GO:0044238 GO:0008236
is_a GO:0003824 GO:0008236
is_a GO:0008233 GO:0008236
part of GO:0043170 GO:0008236
part of GO:0019538 GO:0008236
part of GO:0071704 GO:0008236
is_a GO:0008236 GO:0008240
is_a GO:0008236 GO:0009002
is_a GO:0008236 GO:0070008
is_a GO:0008236 GO:0070009
is_a GO:0008236 GO:0071972
regulates GO:0008236 GO:1900003
regulates GO:0008236 GO:1900004
negatively regulates GO:0008236 GO:1900004
positively regulates GO:0008236 GO:1900005
regulates GO:0008236 GO:1900005
regulates GO:0008236 GO:1902571
regulates GO:0008236 GO:1902571
negatively regulates GO:0008236 GO:1902572
negatively regulates GO:0008236 GO:1902572

1 Synonyms

Name Type
serine protease activity synonym