GO Term : GO:0004823 leucine-tRNA ligase activity GO

Namespace:  molecular_function Obsolete:  false
description  Catalysis of the reaction: L-leucine + ATP + tRNA(Leu) = AMP + diphosphate + 2 H(+) + Leu-tRNA(Leu).

0 Cross References

1 Data Sets

Name URL
InterPro domain GO annotations  

1 Ontology

Name
GO

10158 Ontology Annotations

Class GO Term Gene Name Db
GOAnnotation GO:0004823 157130  
OntologyAnnotation GO:0004823 157130 GO
GOAnnotation GO:0004823 77212  
OntologyAnnotation GO:0004823 77212 GO
GOAnnotation GO:0004823 410808  
OntologyAnnotation GO:0004823 410808 GO
OntologyAnnotation GO:0004823 evm.model.supercontig_113.23 GO
GOAnnotation GO:0004823 evm.TU.supercontig_113.23  
GOAnnotation GO:0004823 evm.TU.supercontig_152.47  
OntologyAnnotation GO:0004823 evm.model.supercontig_152.47 GO
OntologyAnnotation GO:0004823 29765.m000722 GO
GOAnnotation GO:0004823 29765.t000004  
OntologyAnnotation GO:0004823 29842.m003545 GO
GOAnnotation GO:0004823 29842.t000042  
OntologyAnnotation GO:0004823 29876.m000251 GO
GOAnnotation GO:0004823 29876.t000008  
OntologyAnnotation GO:0004823 31633.m000035 GO
GOAnnotation GO:0004823 31633.t000003  
GOAnnotation GO:0004823 Cucsa.044980  
OntologyAnnotation GO:0004823 Cucsa.044980.3 GO
OntologyAnnotation GO:0004823 Cucsa.044980.1 GO
OntologyAnnotation GO:0004823 Cucsa.044980.2 GO
OntologyAnnotation GO:0004823 Cucsa.226900.1 GO
OntologyAnnotation GO:0004823 Cucsa.226900.2 GO
OntologyAnnotation GO:0004823 Cucsa.226900.3 GO
GOAnnotation GO:0004823 Cucsa.226900  
OntologyAnnotation GO:0004823 Cucsa.226900.4 GO
OntologyAnnotation GO:0004823 orange1.1g002411m GO
OntologyAnnotation GO:0004823 orange1.1g002217m GO
GOAnnotation GO:0004823 orange1.1g002217m.g  

9 Parents

Identifier Name Description
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0004812 aminoacyl-tRNA ligase activity Catalysis of the formation of aminoacyl-tRNA from ATP, amino acid, and tRNA with the release of diphosphate and AMP.
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0016874 ligase activity Catalysis of the joining of two substances, or two groups within a single molecule, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
GO:0004823 leucine-tRNA ligase activity Catalysis of the reaction: L-leucine + ATP + tRNA(Leu) = AMP + diphosphate + 2 H(+) + Leu-tRNA(Leu).
GO:0016876 ligase activity, forming aminoacyl-tRNA and related compounds Catalysis of the joining of an amino acid and a nucleic acid (usually tRNA) or poly(ribitol phosphate), with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate. The reaction forms an aminoacyl-tRNA or a related compound.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0016875 ligase activity, forming carbon-oxygen bonds Catalysis of the joining of two molecules via a carbon-oxygen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.

16 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0004812 GO:0004823
is_a GO:0003824 GO:0004823
is_a GO:0016875 GO:0004823
is_a GO:0016876 GO:0004823
part of GO:0008150 GO:0004823
is_a GO:0003674 GO:0004823
is_a GO:0016874 GO:0004823
part of GO:0008152 GO:0004823
regulates GO:0004823 GO:1903633
regulates GO:0004823 GO:1903633
negatively regulates GO:0004823 GO:1903634
negatively regulates GO:0004823 GO:1903634
regulates GO:0004823 GO:1903634
positively regulates GO:0004823 GO:1903635
positively regulates GO:0004823 GO:1903635
regulates GO:0004823 GO:1903635

7 Synonyms

Name Type
L-leucine:tRNALeu ligase (AMP-forming) synonym
leucine translase activity synonym
leucine-tRNA synthetase activity synonym
leucyl-transfer ribonucleate synthetase activity synonym
leucyl-transfer ribonucleic acid synthetase activity synonym
leucyl-transfer RNA synthetase activity synonym
leucyl-tRNA synthetase activity synonym