GO Term : GO:0006614 SRP-dependent cotranslational protein targeting to membrane GO

Namespace:  biological_process Obsolete:  false
description  The targeting of proteins to a membrane that occurs during translation and is dependent upon two key components, the signal-recognition particle (SRP) and the SRP receptor. SRP is a cytosolic particle that transiently binds to the endoplasmic reticulum (ER) signal sequence in a nascent protein, to the large ribosomal unit, and to the SRP receptor in the ER membrane.

0 Cross References

1 Data Sets

Name URL
InterPro domain GO annotations  

1 Ontology

Name
GO

10158 Ontology Annotations

Class GO Term Gene Name Db
GOAnnotation GO:0006614 81201  
OntologyAnnotation GO:0006614 81201 GO
GOAnnotation GO:0006614 81276  
OntologyAnnotation GO:0006614 81276 GO
GOAnnotation GO:0006614 81908  
OntologyAnnotation GO:0006614 81908 GO
GOAnnotation GO:0006614 82182  
OntologyAnnotation GO:0006614 82182 GO
GOAnnotation GO:0006614 234336  
OntologyAnnotation GO:0006614 234336 GO
GOAnnotation GO:0006614 122109  
OntologyAnnotation GO:0006614 122109 GO
GOAnnotation GO:0006614 424503  
OntologyAnnotation GO:0006614 424503 GO
OntologyAnnotation GO:0006614 407935 GO
GOAnnotation GO:0006614 407935  
GOAnnotation GO:0006614 158663  
OntologyAnnotation GO:0006614 158663 GO
GOAnnotation GO:0006614 75660  
OntologyAnnotation GO:0006614 75660 GO
GOAnnotation GO:0006614 77470  
OntologyAnnotation GO:0006614 77470 GO
GOAnnotation GO:0006614 77589  
OntologyAnnotation GO:0006614 77589 GO
OntologyAnnotation GO:0006614 160456 GO
GOAnnotation GO:0006614 160456  
GOAnnotation GO:0006614 413311  
OntologyAnnotation GO:0006614 413311 GO
OntologyAnnotation GO:0006614 417824 GO
GOAnnotation GO:0006614 417824  

66 Parents

Identifier Name Description
GO:0006810 transport The directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore.
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0005622 intracellular The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
GO:0006412 translation The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA. Translation ends with the release of a polypeptide chain from the ribosome.
GO:0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones.
GO:0044237 cellular metabolic process The chemical reactions and pathways by which individual cells transform chemical substances.
GO:0006605 protein targeting The process of targeting specific proteins to particular membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.
GO:0006886 intracellular protein transport The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell.
GO:0006807 nitrogen compound metabolic process The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen, including (but not limited to) nitrogen fixation, nitrification, denitrification, assimilatory/dissimilatory nitrate reduction and the interconversion of nitrogenous organic matter and ammonium.
GO:0015031 protein transport The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0006614 SRP-dependent cotranslational protein targeting to membrane The targeting of proteins to a membrane that occurs during translation and is dependent upon two key components, the signal-recognition particle (SRP) and the SRP receptor. SRP is a cytosolic particle that transiently binds to the endoplasmic reticulum (ER) signal sequence in a nascent protein, to the large ribosomal unit, and to the SRP receptor in the ER membrane.
GO:0019538 protein metabolic process The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification.
GO:0006414 translational elongation The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis.
GO:0071704 organic substance metabolic process The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon.
GO:0046907 intracellular transport The directed movement of substances within a cell.
GO:0044238 primary metabolic process The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
GO:0043043 peptide biosynthetic process The chemical reactions and pathways resulting in the formation of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. This may include the translation of a precursor protein and its subsequent processing into a functional peptide.
GO:0044249 cellular biosynthetic process The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.
GO:0009059 macromolecule biosynthetic process The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0044260 cellular macromolecule metabolic process The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.
GO:0061024 membrane organization A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
GO:0006518 peptide metabolic process The chemical reactions and pathways involving peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another.
GO:0016043 cellular component organization A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component.
GO:0044267 cellular protein metabolic process The chemical reactions and pathways involving a specific protein, rather than of proteins in general, occurring at the level of an individual cell. Includes cellular protein modification.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0008104 protein localization Any process in which a protein is transported to, or maintained in, a specific location.
GO:0006613 cotranslational protein targeting to membrane The targeting of proteins to a membrane that occurs during translation. The transport of most secretory proteins, particularly those with more than 100 amino acids, into the endoplasmic reticulum lumen occurs in this manner, as does the import of some proteins into mitochondria.
GO:0044763 single-organism cellular process Any process that is carried out at the cellular level, occurring within a single organism.
GO:0044699 single-organism process A biological process that involves only one organism.
GO:0051641 cellular localization A localization process that takes place at the cellular level; as a result of a cellular localization process, a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within or in the membrane of a cell.

90 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0006613 GO:0006614
is_a GO:0045047 GO:0006614
has_part GO:0006412 GO:0006614
is_a GO:0016043 GO:0006614
is_a GO:0015031 GO:0006614
is_a GO:0016482 GO:0006614
part of GO:0009987 GO:0006614
has_part GO:0043043 GO:0006614
part of GO:0051641 GO:0006614
occurs in GO:0005622 GO:0006614
has_part GO:0019538 GO:0006614
occurs in GO:0005623 GO:0006614
is_a GO:0009987 GO:0006614
part of GO:0016043 GO:0006614
has_part GO:1901566 GO:0006614
part of GO:0070727 GO:0006614
has_part GO:1901564 GO:0006614
is_a GO:0051179 GO:0006614
is_a GO:1902582 GO:0006614
has_part GO:0009058 GO:0006614
has_part GO:0009059 GO:0006614
part of GO:0008104 GO:0006614
is_a GO:1902580 GO:0006614
has_part GO:0071704 GO:0006614
has_part GO:0044249 GO:0006614
is_a GO:0071702 GO:0006614
is_a GO:0070972 GO:0006614
is_a GO:0072599 GO:0006614
has_part GO:0034641 GO:0006614
is_a GO:0072594 GO:0006614

3 Synonyms

Name Type
ER translocation synonym
SRP-dependent cotranslational membrane targeting synonym
SRP-dependent cotranslational protein-membrane targeting synonym