GO:0003677
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DNA binding
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Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
GO:0005488
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binding
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The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule. |
GO:0003676
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nucleic acid binding
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Interacting selectively and non-covalently with any nucleic acid. |
GO:0007049
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cell cycle
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The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division. |
GO:0007067
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mitotic nuclear division
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A cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell. |
GO:0007076
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mitotic chromosome condensation
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The cell cycle process in which chromatin structure is compacted prior to and during mitosis in eukaryotic cells. |
GO:0051276
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chromosome organization
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A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. This term covers covalent modifications at the molecular level as well as spatial relationships among the major components of a chromosome. |
GO:0007059
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chromosome segregation
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The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles. |
GO:0000278
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mitotic cell cycle
|
Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent. |
GO:0030261
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chromosome condensation
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The progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells. |
GO:0016043
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cellular component organization
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A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component. |
GO:0009987
|
cellular process
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Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. |
GO:0006323
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DNA packaging
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Any process in which DNA and associated proteins are formed into a compact, orderly structure. |
GO:0006996
|
organelle organization
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A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. |
GO:0044763
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single-organism cellular process
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Any process that is carried out at the cellular level, occurring within a single organism. |
GO:0044699
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single-organism process
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A biological process that involves only one organism. |
GO:0071840
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cellular component organization or biogenesis
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A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component. |
GO:1902589
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single-organism organelle organization
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An organelle organization which involves only one organism. |
GO:0008150
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biological_process
|
Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end. |
GO:0003674
|
molecular_function
|
Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions. |
GO:1903047
|
mitotic cell cycle process
|
A process that is part of the mitotic cell cycle. |
GO:0022402
|
cell cycle process
|
The cellular process that ensures successive accurate and complete genome replication and chromosome segregation. |
GO:1901363
|
heterocyclic compound binding
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Interacting selectively and non-covalently with heterocyclic compound. |
GO:0097159
|
organic cyclic compound binding
|
Interacting selectively and non-covalently with an organic cyclic compound, any molecular entity that contains carbon arranged in a cyclic molecular structure. |
GO:0000070
|
mitotic sister chromatid segregation
|
The cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner. One homolog of each morphologic type goes into each of the resulting chromosome sets. |
GO:0000819
|
sister chromatid segregation
|
The cell cycle process in which sister chromatids are organized and then physically separated and apportioned to two or more sets. |
GO:0098813
|
nuclear chromosome segregation
|
The process in which genetic material, in the form of nuclear chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. Nuclear chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles. |
GO:0048285
|
organelle fission
|
The creation of two or more organelles by division of one organelle. |
GO:0000280
|
nuclear division
|
The division of a cell nucleus into two nuclei, with DNA and other nuclear contents distributed between the daughter nuclei. |
GO:0071103
|
DNA conformation change
|
A cellular process that results in a change in the spatial configuration of a DNA molecule. A conformation change can bend DNA, or alter the, twist, writhe, or linking number of a DNA molecule. |