GO Term : GO:0004525 ribonuclease III activity GO

Namespace:  molecular_function Obsolete:  false
description  Catalysis of the endonucleolytic cleavage of RNA with 5'-phosphomonoesters and 3'-OH termini; makes two staggered cuts in both strands of dsRNA, leaving a 3' overhang of 2 nt.

0 Cross References

1 Data Sets

Name URL
InterPro domain GO annotations  

1 Ontology

Name
GO

10158 Ontology Annotations

Class GO Term Gene Name Db
GOAnnotation GO:0004525 432592  
OntologyAnnotation GO:0004525 432592 GO
GOAnnotation GO:0004525 84784  
OntologyAnnotation GO:0004525 84784 GO
GOAnnotation GO:0004525 122841  
OntologyAnnotation GO:0004525 122841 GO
GOAnnotation GO:0004525 86110  
OntologyAnnotation GO:0004525 86110 GO
GOAnnotation GO:0004525 74321  
OntologyAnnotation GO:0004525 74321 GO
OntologyAnnotation GO:0004525 145591 GO
GOAnnotation GO:0004525 145591  
OntologyAnnotation GO:0004525 90770 GO
GOAnnotation GO:0004525 90770  
OntologyAnnotation GO:0004525 429802 GO
GOAnnotation GO:0004525 429802  
GOAnnotation GO:0004525 448444  
OntologyAnnotation GO:0004525 448444 GO
GOAnnotation GO:0004525 411717  
OntologyAnnotation GO:0004525 411717 GO
OntologyAnnotation GO:0004525 97450 GO
GOAnnotation GO:0004525 97450  
GOAnnotation GO:0004525 442454  
OntologyAnnotation GO:0004525 442454 GO
GOAnnotation GO:0004525 444049  
OntologyAnnotation GO:0004525 444049 GO
OntologyAnnotation GO:0004525 evm.TU.contig_40955.1 GO
GOAnnotation GO:0004525 evm.TU.contig_40955  
OntologyAnnotation GO:0004525 evm.model.supercontig_12.267 GO
GOAnnotation GO:0004525 evm.TU.supercontig_12.267  

31 Parents

Identifier Name Description
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016787 hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0044237 cellular metabolic process The chemical reactions and pathways by which individual cells transform chemical substances.
GO:0016788 hydrolase activity, acting on ester bonds Catalysis of the hydrolysis of any ester bond.
GO:0004518 nuclease activity Catalysis of the hydrolysis of ester linkages within nucleic acids.
GO:0004519 endonuclease activity Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks.
GO:0006807 nitrogen compound metabolic process The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen, including (but not limited to) nitrogen fixation, nitrification, denitrification, assimilatory/dissimilatory nitrate reduction and the interconversion of nitrogenous organic matter and ammonium.
GO:0004525 ribonuclease III activity Catalysis of the endonucleolytic cleavage of RNA with 5'-phosphomonoesters and 3'-OH termini; makes two staggered cuts in both strands of dsRNA, leaving a 3' overhang of 2 nt.
GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters Catalysis of the hydrolysis of ester linkages within ribonucleic acids by creating internal breaks to yield 5'-phosphomonoesters.
GO:0006139 nucleobase-containing compound metabolic process Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids.
GO:0071704 organic substance metabolic process The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon.
GO:0004540 ribonuclease activity Catalysis of the hydrolysis of phosphodiester bonds in chains of RNA.
GO:0044238 primary metabolic process The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
GO:0006725 cellular aromatic compound metabolic process The chemical reactions and pathways involving aromatic compounds, any organic compound characterized by one or more planar rings, each of which contains conjugated double bonds and delocalized pi electrons, as carried out by individual cells.
GO:0004521 endoribonuclease activity Catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks.
GO:0016070 RNA metabolic process The cellular chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.
GO:0044260 cellular macromolecule metabolic process The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0090304 nucleic acid metabolic process Any cellular metabolic process involving nucleic acids.
GO:0034641 cellular nitrogen compound metabolic process The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells.
GO:1901360 organic cyclic compound metabolic process The chemical reactions and pathways involving organic cyclic compound.
GO:0046483 heterocycle metabolic process The chemical reactions and pathways involving heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings).
GO:0043170 macromolecule metabolic process The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0090305 nucleic acid phosphodiester bond hydrolysis The nucleic acid metabolic process in which the phosphodiester bonds between nucleotides are cleaved by hydrolysis.
GO:0090501 RNA phosphodiester bond hydrolysis The RNA metabolic process in which the phosphodiester bonds between ribonucleotides are cleaved by hydrolysis.
GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic The chemical reactions and pathways involving the hydrolysis of internal 3',5'-phosphodiester bonds in one or two strands of ribonucleotides.
GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks to yield 5'-phosphomonoesters.

31 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0032296 GO:0004525
is_a GO:0016891 GO:0004525
is_a GO:0016893 GO:0004525
part of GO:0006725 GO:0004525
part of GO:0044260 GO:0004525
part of GO:1901360 GO:0004525
part of GO:0043170 GO:0004525
is_a GO:0003674 GO:0004525
is_a GO:0004521 GO:0004525
part of GO:0006807 GO:0004525
part of GO:0071704 GO:0004525
is_a GO:0004540 GO:0004525
part of GO:0008150 GO:0004525
part of GO:0008152 GO:0004525
part of GO:0016070 GO:0004525
part of GO:0044238 GO:0004525
part of GO:0044237 GO:0004525
is_a GO:0004519 GO:0004525
is_a GO:0004518 GO:0004525
part of GO:0009987 GO:0004525
part of GO:0006139 GO:0004525
part of GO:0090305 GO:0004525
part of GO:0034641 GO:0004525
is_a GO:0003824 GO:0004525
part of GO:0090501 GO:0004525
part of GO:0090502 GO:0004525
part of GO:0090304 GO:0004525
is_a GO:0016788 GO:0004525
part of GO:0046483 GO:0004525
is_a GO:0016787 GO:0004525

3 Synonyms

Name Type
pre-mRNA 3'-end processing endonuclease synonym
ribonuclease 3 activity synonym
RNase III activity synonym