GO Term : GO:0005096 GTPase activator activity GO
Namespace:  molecular_function Obsolete:  false
description  Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.
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0 Cross References

1 Data Sets

Name URL
InterPro domain GO annotations  

1 Ontology

Name
GO

10158 Ontology Annotations

Class GO Term Gene Name Db
OntologyAnnotation GO:0005096 439307 GO
GOAnnotation GO:0005096 439307  
GOAnnotation GO:0005096 124944  
OntologyAnnotation GO:0005096 124944 GO
GOAnnotation GO:0005096 426672  
OntologyAnnotation GO:0005096 426672 GO
GOAnnotation GO:0005096 169243  
OntologyAnnotation GO:0005096 169243 GO
GOAnnotation GO:0005096 68090  
OntologyAnnotation GO:0005096 68090 GO
GOAnnotation GO:0005096 403270  
OntologyAnnotation GO:0005096 403270 GO
GOAnnotation GO:0005096 132360  
OntologyAnnotation GO:0005096 132360 GO
GOAnnotation GO:0005096 441959  
OntologyAnnotation GO:0005096 441959 GO
OntologyAnnotation GO:0005096 413974 GO
GOAnnotation GO:0005096 413974  
OntologyAnnotation GO:0005096 232336 GO
GOAnnotation GO:0005096 232336  
GOAnnotation GO:0005096 102852  
OntologyAnnotation GO:0005096 102852 GO
OntologyAnnotation GO:0005096 404913 GO
GOAnnotation GO:0005096 404913  
GOAnnotation GO:0005096 80545  
OntologyAnnotation GO:0005096 80545 GO
GOAnnotation GO:0005096 107431  
OntologyAnnotation GO:0005096 107431 GO
GOAnnotation GO:0005096 18298  
OntologyAnnotation GO:0005096 18298 GO

32 Parents

Identifier Name Description
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016787 hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.
GO:0005515 protein binding Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
GO:0005488 binding The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.
GO:0003924 GTPase activity Catalysis of the reaction: GTP + H2O = GDP + phosphate.
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0043087 regulation of GTPase activity Any process that modulates the rate of GTP hydrolysis by a GTPase.
GO:0005096 GTPase activator activity Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.
GO:0016817 hydrolase activity, acting on acid anhydrides Catalysis of the hydrolysis of any acid anhydride.
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides Catalysis of the hydrolysis of any acid anhydride which contains phosphorus.
GO:0030234 enzyme regulator activity Binds to and modulates the activity of an enzyme.
GO:0016462 pyrophosphatase activity Catalysis of the hydrolysis of a pyrophosphate bond between two phosphate groups, leaving one phosphate on each of the two fragments.
GO:0043085 positive regulation of catalytic activity Any process that activates or increases the activity of an enzyme.
GO:0050790 regulation of catalytic activity Any process that modulates the activity of an enzyme.
GO:0017111 nucleoside-triphosphatase activity Catalysis of the reaction: a nucleoside triphosphate + H2O = nucleoside diphosphate + phosphate.
GO:0008047 enzyme activator activity Binds to and increases the activity of an enzyme.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0065007 biological regulation Any process that modulates a measurable attribute of any biological process, quality or function.
GO:0050789 regulation of biological process Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.
GO:0065009 regulation of molecular function Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.
GO:0048518 positive regulation of biological process Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0044093 positive regulation of molecular function Any process that activates or increases the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.
GO:0009893 positive regulation of metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.
GO:0098772 molecular function regulator A molecular function that modulates the activity of a gene product or complex. Examples include enzyme regulators and channel regulators.
GO:0019899 enzyme binding Interacting selectively and non-covalently with any enzyme.
GO:0060589 nucleoside-triphosphatase regulator activity Modulates the rate of NTP hydrolysis by a NTPase.
GO:0051336 regulation of hydrolase activity Any process that modulates the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.
GO:0051345 positive regulation of hydrolase activity Any process that activates or increases the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds.

44 Relations

Relationship
Parent Term . Identifier
Child Term . Identifier
is_a GO:0030695 GO:0005096
part of GO:0043547 GO:0005096
is_a GO:0008047 GO:0005096
positively regulates GO:0003924 GO:0005096
regulates GO:0016818 GO:0005096
part of GO:0050789 GO:0005096
part of GO:0019222 GO:0005096
regulates GO:0016817 GO:0005096
part of GO:0051336 GO:0005096
regulates GO:0008150 GO:0005096
part of GO:0008150 GO:0005096
positively regulates GO:0003674 GO:0005096
part of GO:0065007 GO:0005096
regulates GO:0008152 GO:0005096
has_part GO:0005488 GO:0005096
regulates GO:0017111 GO:0005096
regulates GO:0016462 GO:0005096
positively regulates GO:0008152 GO:0005096
positively regulates GO:0016787 GO:0005096
positively regulates GO:0008150 GO:0005096
part of GO:0051345 GO:0005096
regulates GO:0003674 GO:0005096
positively regulates GO:0017111 GO:0005096
positively regulates GO:0016462 GO:0005096
part of GO:0050790 GO:0005096
is_a GO:0003674 GO:0005096
part of GO:0043087 GO:0005096
part of GO:0043085 GO:0005096
positively regulates GO:0003824 GO:0005096
part of GO:0048518 GO:0005096

29 Synonyms

Name Type
Ran GTPase activator activity synonym
Ran GAP activity synonym
Rap GAP activity synonym
RanGAP synonym
Ras GAP activity synonym
Rap GTPase activator activity synonym
Rho GAP activity synonym
Ras GTPase activator activity synonym
Sar GAP activity synonym
Rho GTPase activator activity synonym
GO:0005097 alt_id
Sar GTPase activator activity synonym
GO:0005099 alt_id
GO:0005098 alt_id
GO:0005101 alt_id
GO:0005100 alt_id
GO:0017123 alt_id
GO:0008060 alt_id
GO:0046582 alt_id
GO:0030675 alt_id
ARF GAP activity synonym
GAP activity synonym
ARF GTPase activator activity synonym
Rab GTPase activator activity synonym
Rab GAP activity synonym
Rac GTPase activator activity synonym
Rac GAP activity synonym
Ral GTPase activator activity synonym
Ral GAP activity synonym