GO Term : GO:0006506 GPI anchor biosynthetic process GO

Namespace:  biological_process Obsolete:  false
description  The chemical reactions and pathways resulting in the formation of a glycosylphosphatidylinositol (GPI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The phosphatidylinositol group is linked via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked to the protein via an ethanolamine phosphate group, its amino group forming an amide linkage with the C-terminal carboxyl of the protein. Some GPI anchors have variants on this canonical linkage.

0 Cross References

1 Data Sets

Name URL
InterPro domain GO annotations  

1 Ontology

Name
GO

10158 Ontology Annotations

Class GO Term Gene Name Db
GOAnnotation GO:0006506 268247  
OntologyAnnotation GO:0006506 268247 GO
OntologyAnnotation GO:0006506 117327 GO
GOAnnotation GO:0006506 117327  
GOAnnotation GO:0006506 406788  
OntologyAnnotation GO:0006506 406788 GO
OntologyAnnotation GO:0006506 439394 GO
GOAnnotation GO:0006506 439394  
OntologyAnnotation GO:0006506 121519 GO
GOAnnotation GO:0006506 121519  
GOAnnotation GO:0006506 437591  
OntologyAnnotation GO:0006506 437591 GO
OntologyAnnotation GO:0006506 90874 GO
GOAnnotation GO:0006506 90874  
GOAnnotation GO:0006506 132847  
OntologyAnnotation GO:0006506 132847 GO
GOAnnotation GO:0006506 405321  
OntologyAnnotation GO:0006506 405321 GO
GOAnnotation GO:0006506 416473  
OntologyAnnotation GO:0006506 416473 GO
OntologyAnnotation GO:0006506 evm.model.supercontig_14.108 GO
GOAnnotation GO:0006506 evm.TU.supercontig_14.108  
OntologyAnnotation GO:0006506 evm.model.supercontig_14.89 GO
GOAnnotation GO:0006506 evm.TU.supercontig_14.89  
OntologyAnnotation GO:0006506 evm.model.supercontig_17.6 GO
GOAnnotation GO:0006506 evm.TU.supercontig_17.6  
GOAnnotation GO:0006506 evm.TU.supercontig_1833.2  
OntologyAnnotation GO:0006506 evm.model.supercontig_1833.2 GO
OntologyAnnotation GO:0006506 evm.model.supercontig_34.32 GO
GOAnnotation GO:0006506 evm.TU.supercontig_34.32  

49 Parents

Identifier Name Description
GO:0006629 lipid metabolic process The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones.
GO:0008654 phospholipid biosynthetic process The chemical reactions and pathways resulting in the formation of phospholipids, any lipid containing phosphoric acid as a mono- or diester.
GO:0006796 phosphate-containing compound metabolic process The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid.
GO:0044237 cellular metabolic process The chemical reactions and pathways by which individual cells transform chemical substances.
GO:0008610 lipid biosynthetic process The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.
GO:0006506 GPI anchor biosynthetic process The chemical reactions and pathways resulting in the formation of a glycosylphosphatidylinositol (GPI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The phosphatidylinositol group is linked via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked to the protein via an ethanolamine phosphate group, its amino group forming an amide linkage with the C-terminal carboxyl of the protein. Some GPI anchors have variants on this canonical linkage.
GO:0019538 protein metabolic process The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification.
GO:0006505 GPI anchor metabolic process The chemical reactions and pathways involving glycosylphosphatidylinositol anchors, molecular mechanisms for attaching membrane proteins to the lipid bilayer of cell membranes. Structurally they consist of a molecule of phosphatidylinositol to which is linked, via the C-6 hydroxyl of the inositol, a carbohydrate chain. This chain is in turn linked to the protein through an ethanolamine phosphate group, the amino group of which is in amide linkage with the C-terminal carboxyl of the protein chain, the phosphate group being esterified to the C-6 hydroxyl of the terminal mannose of the core carbohydrate chain.
GO:0006464 cellular protein modification process The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) occurring at the level of an individual cell. Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).
GO:0071704 organic substance metabolic process The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon.
GO:0043412 macromolecule modification The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule, resulting in a change in its properties.
GO:0006661 phosphatidylinositol biosynthetic process The chemical reactions and pathways resulting in the formation of phosphatidylinositol, any glycophospholipid in which the sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol.
GO:0046488 phosphatidylinositol metabolic process The chemical reactions and pathways involving phosphatidylinositol, any glycophospholipid in which a sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol.
GO:0044238 primary metabolic process The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
GO:0006644 phospholipid metabolic process The chemical reactions and pathways involving phospholipids, any lipid containing phosphoric acid as a mono- or diester.
GO:0045017 glycerolipid biosynthetic process The chemical reactions and pathways resulting in the formation of glycerolipids, any lipid with a glycerol backbone.
GO:1901137 carbohydrate derivative biosynthetic process The chemical reactions and pathways resulting in the formation of carbohydrate derivative.
GO:0044249 cellular biosynthetic process The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.
GO:0009059 macromolecule biosynthetic process The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0009247 glycolipid biosynthetic process The chemical reactions and pathways resulting in the formation of glycolipid, a class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide).
GO:0006650 glycerophospholipid metabolic process The chemical reactions and pathways involving glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue.
GO:0044260 cellular macromolecule metabolic process The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.
GO:0044267 cellular protein metabolic process The chemical reactions and pathways involving a specific protein, rather than of proteins in general, occurring at the level of an individual cell. Includes cellular protein modification.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0042158 lipoprotein biosynthetic process The chemical reactions and pathways resulting in the formation of any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids.
GO:0006793 phosphorus metabolic process The chemical reactions and pathways involving the nonmetallic element phosphorus or compounds that contain phosphorus, usually in the form of a phosphate group (PO4).
GO:0044255 cellular lipid metabolic process The chemical reactions and pathways involving lipids, as carried out by individual cells.
GO:0042157 lipoprotein metabolic process The chemical reactions and pathways involving any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids.

69 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0006497 GO:0006506
is_a GO:0009247 GO:0006506
is_a GO:0006661 GO:0006506
is_a GO:0006505 GO:0006506
is_a GO:0044267 GO:0006506
is_a GO:0043412 GO:0006506
is_a GO:0046486 GO:0006506
is_a GO:0006629 GO:0006506
is_a GO:0046488 GO:0006506
part of GO:0043170 GO:0006506
is_a GO:1903509 GO:0006506
is_a GO:0006464 GO:0006506
is_a GO:0006664 GO:0006506
is_a GO:0009058 GO:0006506
part of GO:0019538 GO:0006506
is_a GO:0043170 GO:0006506
is_a GO:0044260 GO:0006506
part of GO:0042158 GO:0006506
part of GO:0042157 GO:0006506
part of GO:1901576 GO:0006506
is_a GO:0044699 GO:0006506
is_a GO:0046474 GO:0006506
is_a GO:0044255 GO:0006506
is_a GO:0006650 GO:0006506
part of GO:0044260 GO:0006506
is_a GO:0008152 GO:0006506
is_a GO:0008150 GO:0006506
part of GO:0009058 GO:0006506
part of GO:0009059 GO:0006506
is_a GO:0019637 GO:0006506

9 Synonyms

Name Type
GPI anchor synthesis synonym
GPI anchor formation synonym
GPI/GSI anchor biosynthetic process synonym
GPI/GSI anchor biosynthesis synonym
GO:0015998 alt_id
glycosylphosphatidylinositol biosynthetic process synonym
glycosylphosphatidylinositol biosynthesis synonym
GPI anchor biosynthesis synonym
GPI anchor anabolism synonym