GO Term : GO:0005730 nucleolus GO

Namespace:  cellular_component Obsolete:  false
description  A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.

0 Cross References

1 Data Sets

Name URL
InterPro domain GO annotations  

1 Ontology

Name
GO

10158 Ontology Annotations

Class GO Term Gene Name Db
OntologyAnnotation GO:0005730 159569 GO
GOAnnotation GO:0005730 159569  
GOAnnotation GO:0005730 21658  
OntologyAnnotation GO:0005730 21658 GO
GOAnnotation GO:0005730 77105  
OntologyAnnotation GO:0005730 77105 GO
GOAnnotation GO:0005730 89228  
OntologyAnnotation GO:0005730 89228 GO
GOAnnotation GO:0005730 231970  
OntologyAnnotation GO:0005730 231970 GO
OntologyAnnotation GO:0005730 98161 GO
GOAnnotation GO:0005730 98161  
GOAnnotation GO:0005730 173778  
OntologyAnnotation GO:0005730 173778 GO
OntologyAnnotation GO:0005730 166421 GO
GOAnnotation GO:0005730 166421  
OntologyAnnotation GO:0005730 evm.model.supercontig_108.65 GO
GOAnnotation GO:0005730 evm.TU.supercontig_108.65  
OntologyAnnotation GO:0005730 evm.model.supercontig_3.248 GO
GOAnnotation GO:0005730 evm.TU.supercontig_3.248  
OntologyAnnotation GO:0005730 evm.model.supercontig_56.89 GO
GOAnnotation GO:0005730 evm.TU.supercontig_56.89  
OntologyAnnotation GO:0005730 evm.model.supercontig_75.43 GO
GOAnnotation GO:0005730 evm.TU.supercontig_75.43  
OntologyAnnotation GO:0005730 evm.model.supercontig_80.41 GO
GOAnnotation GO:0005730 evm.TU.supercontig_80.41  
OntologyAnnotation GO:0005730 evm.model.supercontig_9.148 GO
GOAnnotation GO:0005730 evm.TU.supercontig_9.148  
OntologyAnnotation GO:0005730 28095.m000097 GO
GOAnnotation GO:0005730 28095.t000004  

20 Parents

Identifier Name Description
GO:0005634 nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
GO:0005622 intracellular The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
GO:0005730 nucleolus A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
GO:0043231 intracellular membrane-bounded organelle Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
GO:0044464 cell part Any constituent part of a cell, the basic structural and functional unit of all organisms.
GO:0044424 intracellular part Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
GO:0005575 cellular_component The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.
GO:0005623 cell The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
GO:0044428 nuclear part Any constituent part of the nucleus, a membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated.
GO:0043227 membrane-bounded organelle Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
GO:0043226 organelle Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane.
GO:0043229 intracellular organelle Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
GO:0044422 organelle part Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.
GO:0044446 intracellular organelle part A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.
GO:0031974 membrane-enclosed lumen The enclosed volume within a sealed membrane or between two sealed membranes. Encompasses the volume enclosed by the membranes of a particular organelle, e.g. endoplasmic reticulum lumen, or the space between the two lipid bilayers of a double membrane surrounding an organelle, e.g. nuclear envelope lumen.
GO:0070013 intracellular organelle lumen An organelle lumen that is part of an intracellular organelle.
GO:0043233 organelle lumen The internal volume enclosed by the membranes of a particular organelle; includes the volume enclosed by a single organelle membrane, e.g. endoplasmic reticulum lumen, or the volume enclosed by the innermost of the two lipid bilayers of an organelle envelope, e.g. nuclear lumen.
GO:0031981 nuclear lumen The volume enclosed by the nuclear inner membrane.
GO:0043228 non-membrane-bounded organelle Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes.
GO:0043232 intracellular non-membrane-bounded organelle Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes.

53 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
part of GO:0005730 GO:0000120
part of GO:0005730 GO:0000500
part of GO:0005730 GO:0001650
part of GO:0005730 GO:0001651
part of GO:0005730 GO:0001652
part of GO:0005730 GO:0005655
part of GO:0005730 GO:0005655
part of GO:0005730 GO:0005668
is_a GO:0043232 GO:0005730
is_a GO:0044428 GO:0005730
part of GO:0031981 GO:0005730
part of GO:0005634 GO:0005730
is_a GO:0044446 GO:0005730
is_a GO:0044424 GO:0005730
part of GO:0070013 GO:0005730
part of GO:0043231 GO:0005730
part of GO:0043227 GO:0005730
part of GO:0043226 GO:0005730
is_a GO:0005575 GO:0005730
is_a GO:0044464 GO:0005730
is_a GO:0044422 GO:0005730
part of GO:0043229 GO:0005730
part of GO:0005622 GO:0005730
part of GO:0005623 GO:0005730
is_a GO:0043226 GO:0005730
is_a GO:0043229 GO:0005730
is_a GO:0043228 GO:0005730
part of GO:0031974 GO:0005730
part of GO:0044428 GO:0005730
part of GO:0043233 GO:0005730

0 Synonyms