Protein Domain : IPR011383

Type:  Family Name:  N-lysine methyltransferase SETD6
Description:  SET domain methyltransferases can be involved both in translational and transcriptional roles. N-lysine methyltransferase SETD6 is a SET domain protein that specifically monomethylates 'Lys-310' of the RELA subunit of NF-kappa-B complex, leading to down-regulation of NF-kappa-B transcription factor activity []. Homologues in yeast monomethylate 60S ribosomal protein L42 (RPL42A and RPL42B) at 'Lys-55' [, ]. Short Name:  N-lys_methylase_SETD6

0 Child Features

2 Contains

DB identifier Type Name
IPR015353 Domain Rubisco LSMT, substrate-binding domain
IPR001214 Domain SET domain

1 Cross References

Identifier
PIRSF011771

0 Found In

2 GO Annotations

GO Term Gene Name
GO:0016279 IPR011383
GO:0018026 IPR011383

2 Ontology Annotations

GO Term Gene Name
GO:0016279 IPR011383
GO:0018026 IPR011383

0 Parent Features

265 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
29983.m003299 B9RWA1 PAC:16815064 Ricinus communis 471  
orange1.1g041727m PAC:18103684 Citrus sinensis 519  
Thhalv10006013m V4LWZ8 PAC:20190140 Eutrema salsugineum 406  
Lus10026538 PAC:23164300 Linum usitatissimum 518  
Potri.004G135700.1 A0A2K2AU91 PAC:26992936 Populus trichocarpa 494  
Gorai.012G045900.1 A0A0D2RXU0 PAC:26828910 Gossypium raimondii 538  
Migut.F00913.1.p PAC:28932148 Mimulus guttatus 512  
Cagra.0925s0071.1.p PAC:28917149 Capsella grandiflora 530  
Glyma.10G176100.1.p K7LK18 PAC:30476718 Glycine max 447  
Brara.I03889.1.p A0A397Y9H2 PAC:30641083 Brassica rapa FPsc 508  
Medtr1g077040.1 A0A072VLJ5 PAC:31095355 Medicago truncatula 497  
Medtr1g077040.2 A0A072VN72 PAC:31095356 Medicago truncatula 414  
SapurV1A.0185s0050.1.p PAC:31435159 Salix purpurea 493  
Spipo0G0075000 PAC:31507788 Spirodela polyrhiza 494  
evm_27.model.AmTr_v1.0_scaffold00071.149 U5DEY2 PAC:31561181 Amborella trichopoda 552  
Traes_3B_A1EE50B97.1 PAC:31744433 Triticum aestivum 518  
Prupe.4G288100.11.p A0A251PSN9 PAC:32090853 Prunus persica 548  
Prupe.4G288100.2.p A0A251PSS0 PAC:32090857 Prunus persica 417  
Prupe.4G288100.3.p A0A251PSS0 PAC:32090858 Prunus persica 417  
Prupe.4G288100.6.p A0A251PSN9 PAC:32090854 Prunus persica 548  
Prupe.4G288100.10.p A0A251PSR0 PAC:32090855 Prunus persica 539  
Prupe.4G288100.4.p A0A251PSS0 PAC:32090856 Prunus persica 417  
Prupe.4G288100.9.p A0A251PSS0 PAC:32090861 Prunus persica 417  
Prupe.4G288100.8.p A0A251PSS0 PAC:32090862 Prunus persica 417  
Prupe.4G288100.5.p A0A251PSS0 PAC:32090859 Prunus persica 417  
Prupe.4G288100.7.p A0A251PSS0 PAC:32090860 Prunus persica 417  
Manes.13G154300.2.p A0A251K0R9 PAC:32338586 Manihot esculenta 491  
Manes.13G154300.1.p A0A251K0R9 PAC:32338585 Manihot esculenta 491  
Pahal.E00737.1 A0A2S3HPL2 PAC:32495584 Panicum hallii 490  
Kalax.0042s0060.1.p PAC:32540760 Kalanchoe laxiflora 494  

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            16096273
            21131967
            20444689