Protein Domain : IPR003352

Type:  Domain Name:  Phosphotransferase system, EIIC
Description:  The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. The PTS catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. The general mechanism of the PTS is the following: a phosphoryl group from phosphoenolpyruvate (PEP) is transferred to enzyme-I (EI) of PTS which in turn transfers it to a phosphoryl carrier protein (HPr). Phospho-HPr then transfers the phosphoryl group to a sugar-specific permease which consists of at least three structurally distinct domains (IIA, IIB, and IIC) [] which can either be fused together in a single polypeptide chain or exist as two or three interactive chains, formerly called enzymes II (EII) and III (EIII). The IIC domain catalyzes the transfer of a phosphoryl group from IIB to the sugar substrate.PTS systems commonly occur in bacteria. An archaeal version has also been discovered []. This entry identifies both the bacterial family members and archaeal homologues. Short Name:  PTS_EIIC
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3 Child Features

DB identifier Type Name
IPR013013 Domain Phosphotransferase system, EIIC component, type 1
IPR013014 Domain Phosphotransferase system, EIIC component, type 2
IPR004501 Domain Phosphotransferase system, EIIC component, type 3

0 Contains

2 Cross Referencess

Identifier
PF02378
PF13303

6 Found Ins

DB identifier Type Name
IPR011299 Domain PTS system glucose-specific IIBC component
IPR011296 Domain Phosphotransferase system, trehalose-specific IIBC component
IPR010974 Domain Phosphotransferase system, N-acetylglucosamine-specific IIBC component
IPR011297 Family Phosphotransferase system, beta-glucoside-specific IIABC component
IPR010973 Domain Phosphotransferase system, sucrose-specific IIBC component
IPR011300 Domain Phosphotransferase system, IIBC component

3 GO Annotations

GO Term Gene Name
GO:0008982 IPR003352
GO:0009401 IPR003352
GO:0016020 IPR003352

3 Ontology Annotations

GO Term Gene Name
GO:0008982 IPR003352
GO:0009401 IPR003352
GO:0016020 IPR003352

0 Parent Features

14 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
Araha.11756s0077.1.p PAC:28856530 Arabidopsis halleri 478  
Araha.11756s0242.1.p PAC:28856383 Arabidopsis halleri 564  
Brdisv1pangenome1005610m.p PAC:33624718 Brachypodium distachyon Pangenome 930  
Brdisv1pangenome1006693m.p PAC:33621128 Brachypodium distachyon Pangenome 640  
Brdisv1pangenome1007266m.p PAC:33641287 Brachypodium distachyon Pangenome 970  
Brdisv1pangenome1007360m.p PAC:33622517 Brachypodium distachyon Pangenome 924  
Brdisv1pangenome1008533m.p PAC:33622128 Brachypodium distachyon Pangenome 947  
Brdisv1pangenome1010718m.p PAC:33655386 Brachypodium distachyon Pangenome 565  
Brdisv1BdTR11A1029459m.p PAC:35677832 Brachypodium distachyon BdTR11a 1082  
Brdisv1BdTR11A1044329m.p PAC:35696163 Brachypodium distachyon BdTR11a 1038  
Brdisv1BdTR11A1040147m.p PAC:35691612 Brachypodium distachyon BdTR11a 942  
Brdisv1BdTR11A1040317m.p PAC:35687804 Brachypodium distachyon BdTR11a 832  
Brdisv1BdTR11A1041495m.p PAC:35695100 Brachypodium distachyon BdTR11a 640  
Brdisv1BdTR11A1042114m.p PAC:35688106 Brachypodium distachyon BdTR11a 970  

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            1537788
            22493022